PMID: 8469788Jan 1, 1993Paper

Preliminary screening of the relationship of serum lipids to survival of chronic dialysis patients

Renal Failure
J A D'EliaR W Nesto

Abstract

To assess the predictive value of serum lipid measurements in dialysis patients once the initial decrease on early dialysis had occurred, we obtained random serum cholesterol and triglyceride levels in stable, chronic dialysis patients who were then followed up to 9 years. Derived LDL (DLDL) was estimated by the Friedewald formula, calculated for all HDL levels between 30 and 45 mg/dL, and evaluated statistically against a panel of vascular disease markers, including clinical assessment for coronary, peripheral, and cerebrovascular disease; ECG, both standard and ambulatory; two-dimensional echocardiogram; and medications. Survival was calculated from entry (not dialysis onset) for 58 hemodialysis and 33 peritoneal dialysis patients. The 91 patients (49 males, 74 diabetics) were divided by cholesterol level (> or = 175 mg/dL = 53, < 175 = 38), triglyceride (> or = 175 mg/dL = 55, < 175 = 36), and DLDL (> or = 75 = 58, < 75 = 24). High total cholesterol was present in a larger proportion of females than low cholesterol, but groups were not different with respect to all vascular determinants, including survival (mean = 33.4 months vs. 43.2, p = NS). High vs. low triglyceride groups were not different with respect to vascular indi...Continue Reading

References

Jan 1, 1992·Diabetes Care·J L LarsenW C Duckworth
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Citations

May 1, 1996·Kidney International·P S ParfreyP E Barre
Jun 26, 2001·Journal of the American Society of Nephrology : JASN·Austin G Stack, Wendy E Bloembergen
Apr 30, 2005·International Journal of Cardiology·John A D'EliaGeoffrey H Tofler

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