PMID: 8607006Nov 1, 1995Paper

Premalignant changes in ulcerative colitis

Seminars in Surgical Oncology
J B NixonA H Mirza

Abstract

Colitis-associated carcinoma is often associated with, or preceded by, noninvasive epithelial neoplastic changes termed dysplasia. Surveillance colonoscopy with biopsies looking for dysplasia is now standard practice in the management of the cancer problem in ulcerative colitis. However, this practice continues to have a number of limitations and problems that need to be understood by surgeons who may be referring such patients. A number of recent reports indicate that colitis associated carcinoma is predominantly left-sided and incorporation of this distribution in the surveillance methods merits consideration. The molecular and genetic abnormalities involved in the pathogenesis of colitis associated neoplasia are being actively investigated and may yield supplementary methods to better define individual patient risk.

References

Dec 15, 1991·The New England Journal of Medicine·M J ThunC W Heath
Jul 1, 1991·British Journal of Cancer·S M BellP Quirke
Aug 1, 1990·Gastroenterology·G C BurmerP S Rabinovitch
Nov 1, 1990·The New England Journal of Medicine·A EkbomH O Adami
Jan 1, 1985·Gastroenterology·G M AndersonD J Cohen
Oct 1, 1986·Cancer·S H Mir-MadjlessiG J Beck
Dec 1, 1985·Gastroenterology·E RosenstockB H Sullivan
Jan 1, 1983·Digestive Diseases and Sciences·J H ButtJ K Ritchie
Jan 8, 1994·Lancet
Jul 1, 1994·Cleveland Clinic Journal of Medicine·B A Lashner
Aug 1, 1994·Gastroenterology·S E KernK W Kinzler
May 6, 1993·The New England Journal of Medicine·F M GiardielloG J Offerhaus
Jan 1, 1993·Journal of Cancer Research and Clinical Oncology·B A Lashner
Oct 28, 1993·The New England Journal of Medicine·C C Harris, M Hollstein
May 1, 1964·Cancer·M B GOLDGRABER, J B KIRSNER

❮ Previous
Next ❯

Citations

Mar 29, 2001·Current Surgery·K Cabrera, R W. Schwartz
Mar 29, 2001·Current Surgery·K Cabrera, R W. Schwartz
Mar 1, 1997·Baillière's Clinical Gastroenterology·F A Macrae, P S Bhathal
Jun 24, 2017·Journal of Investigative Medicine High Impact Case Reports·Vivek KumarJonathan Harris

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

© 2021 Meta ULC. All rights reserved