Premalignant lesions of cholangiocarcinoma: characteristics on ultrasonography and MRI

Abdominal Radiology
Surachate SiripongsakunSaowanee Srittanapong

Abstract

Cholangiocarcinoma (CCA) is an aggressive malignancy with high prevalence rate in Asia. The CCA premalignant lesions, including Biliary intraepithelial neoplasia (Bil-IN) and Intraductal papillary neoplasm of biliary tract (IPNB), share a common carcinogenesis; however, on imaging, patterns of presentation are different. Patterns and imaging characteristics on ultrasonography (US) and Magnetic resonance imaging (MRI) of both Bil-IN and IPNB are reported herein. In this retrospective study of imaging findings in premalignant CCA, pathology-proven cases of Bil-IN and IPNB at Chulabhorn Hospital were analyzed. Demographics, locations of lesions, imaging characteristics of both Bil-IN and IPNB were assessed, compared, and described. Twenty-one premalignant lesions, 13 Bil-INs and 8 IPNBs, from 18 patients were included. Both Bil-IN and IPNB lesions were found more commonly at the right than left intrahepatic ducts (66.7% vs. 33.3%), and had more peripheral than central locations (85.7% vs. 14.3%). On US, Bil-IN commonly presented as focal bile duct dilatation (76.9%), whereas IPNB was more variable with hyperechoic nodules (37.5%), focal bile duct dilatation (37.5%), and diffuse bile duct dilatation with intraductal nodules (25%). ...Continue Reading

References

Nov 13, 2003·Acta Tropica·P Jongsuksuntigul, T Imsomboon
Apr 15, 2008·Current Opinion in Gastroenterology·Banchob Sripa, Chawalit Pairojkul
Sep 6, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·S A KhanS D Taylor-Robinson
Oct 16, 2008·Virchows Archiv : an International Journal of Pathology·Kee-Taek JangJae Hoon Lim
Apr 8, 2009·The Lancet Oncology·Véronique BouvardUNKNOWN WHO International Agency for Research on Cancer Monograph Working Group
May 19, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Yong Eun ChungSun Young Choi
Jul 27, 2010·Acta Tropica·Banchob SripaPaul J Brindley
Oct 31, 2009·World Journal of Hepatology·Yasuni NakanumaKenichi Harada
Sep 29, 2011·The American Journal of Gastroenterology·Kwang Min KimJae Hoon Lim
Feb 22, 2012·World Journal of Gastroenterology : WJG·Ahmad Ramzi YusoffZuraidah Mahmud Siti
Oct 22, 2013·Gastroenterology·Sumera Rizvi, Gregory J Gores
Jan 22, 2014·Journal of Hepato-biliary-pancreatic Sciences·Shinichi AishimaYoshinao Oda
Jun 21, 2014·International Journal of Hepatology·Masayuki OhtsukaMasaru Miyazaki
Jul 10, 2014·Journal of Clinical Pathology·Stefano Serra
Jun 10, 2015·BMC Cancer·Narong KhuntikeoUNKNOWN CASCAP investigators
Nov 12, 2015·World Journal of Hepatology·Mark EttelRuliang Xu
Oct 28, 2016·Archives of Pathology & Laboratory Medicine·Sanaz Ainechi, Hwajeong Lee
Mar 9, 2017·Abdominal Radiology·Irai S OliveiraKarthik Ganesan
Aug 9, 2017·Gut and Liver·Piyapan PrueksapanichRungsun Rerknimitr
Aug 30, 2017·International Journal of General Medicine·Thomas HughesSimon D Taylor-Robinson

❮ Previous
Next ❯

Citations

May 11, 2021·World Journal of Clinical Cases·Dan YiSong-Yang Liu
Sep 11, 2021·Nature Reviews. Disease Primers·Paul J BrindleyGregory J Gores
Jan 5, 2022·Liver International : Official Journal of the International Association for the Study of the Liver·Elvire DesjonqueresJean-Charles Nault

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.