PMID: 9170488Jun 1, 1997Paper

Premature rupture of membranes at term: a meta-analysis of three management schemes

Obstetrics and Gynecology
Ellen Mozurkewich, F M Wolf

Abstract

To compare rates of cesarean birth, endometritis, chorioamnionitis, and serious neonatal infections among pregnancies complicated by premature rupture of membranes (PROM) at term and managed by immediate oxytocin induction, by conservative management (or delayed oxytocin induction), or by vaginal (or endocervical) prostaglandin E2, gel, suppositories, or tablets. The English-language literature in MLD, LINE and other databases was searched through April 1996 using the terms "fetal membranes," "premature rupture," and "term." We included randomized trials comparing two or more management schemes for PROM at term. Twenty-three studies with a total of 7493 subjects met the inclusion criteria and were included for analysis. Data regarding chorioamnionitis, endometritis, neonatal infections, and cesarean delivery were extracted. Meta-analyses were performed for the three interventions for these outcomes of interest using the Der-Simonian and Laird and Mantel-Haenszel techniques to estimate the pooled odds ratios (ORs). No statistically significant differences in cesarean deliveries or neonatal infections were noted among management schemes. Vaginal prostaglandins resulted in more chorioamnionitis than immediate oxytocin (OR 1.55, 95...Continue Reading

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Citations

Jun 11, 1999·Obstetrics and Gynecology·D PelegD Farine
May 15, 2010·Taiwanese Journal of Obstetrics & Gynecology·Cigdem KuntLeyla Mollamahmutoglu
Nov 26, 1999·Clinical Obstetrics and Gynecology·E Mozurkewich
Nov 11, 1999·The Australian & New Zealand Journal of Obstetrics & Gynaecology·D AkyolK Yüksel
Oct 22, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Ashraf F NabhanMohamed Elkadi
Apr 8, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Irena B CabreraWilliam E Scorza
Oct 21, 2016·Archives of Gynecology and Obstetrics·Eran AshwalLiran Hiersch
Apr 10, 2009·Gynécologie, obstétrique & fertilité·G Kayem, F Maillard
Oct 21, 2016·Archives of Gynecology and Obstetrics·Dana Sadeh-MestechkinTal Biron-Shental
Aug 4, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Liran HierschEran Ashwal
Jun 30, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Yossef EzraNathan Rojansky
Jan 5, 2017·The Cochrane Database of Systematic Reviews·Philippa MiddletonCaroline A Crowther
Feb 23, 2018·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Kassam MahomedChristopher R Weekes
Feb 5, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·E MozurkewichV J King
Apr 23, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Sidsel Hein IngerslevHans Jakob Ingerslev
Sep 28, 2010·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Kui LiHuixia Yang
May 30, 2017·Gynécologie, Obstétrique, Fertilité & Sénologie·C HuretD Gallot

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