Prenatal and early childhood exposure to phthalates and childhood behavior at age 7 years.

Environment International
Sharon DanielPam Factor-Litvak

Abstract

Emerging evidence suggests that phthalate exposure may be associated with behavior problems in children and that these associations may be sex specific. In a follow up study of 411 inner-city minority mothers and their children, mono-n-butyl phthalate (MnBP), monobenzyl phthalate (MBzP), monoisobutyl phthalate (MiBP), monethyl phthalate (MEP) and four di-2-ethylhexyl phthalate metabolites (DEHP) were quantified in maternal urine samples collected during the third trimester and in child urine samples at ages 3 and 5 years. The Conners' Parent Rating Scale-Revised: Long Form (CPRS) and Child Behavior Checklist (CBCL) were administered to the mothers to assess children's behavior problems at 7 years of age. The analysis included children with available measures of CBCL, CPRS and phthalates measured in maternal urine. We performed both Quasi-Poisson regression and a mixture analysis using Weighted Quantile Sum(WQS) regression to assess the risk for CPRS scores and for internalizing and externalizing behaviors (from the CBCL) following intra-uterine exposure to the phthalate metabolites for boys and girls separately. Among boys, increases in in anxious-shy behaviors were associated with prenatal exposure to MBzP (Mean Ratio [MR] = 1...Continue Reading

References

Jan 1, 1992·Hormone Research·B S McEwen
Dec 1, 1986·Environmental Health Perspectives·R H HintonJ W Bridges
Aug 13, 1998·Journal of Abnormal Child Psychology·C K ConnersJ N Epstein
Dec 26, 2001·Annual Review of Psychology·Robert H Bradley, Robert F Corwyn
May 11, 2002·The Proceedings of the Nutrition Society·Patricia E Wainwright
May 11, 2002·Environmental Health Perspectives·Jane A HoppinDonna D Baird
Sep 7, 2002·Toxicological Sciences : an Official Journal of the Society of Toxicology·John C O'ConnorGregory S Ladics
Nov 5, 2002·The Journal of Clinical Endocrinology and Metabolism·Kenji MoriyamaKazuwa Nakao
Feb 8, 2003·Environmental Health Perspectives·Frederica P PereraRobin M Whyatt
Nov 5, 2003·Environmental Health Perspectives·Jennifer J AdibiRobin M Whyatt
Dec 8, 2004·Environmental Health Perspectives·Russ HauserAntonia M Calafat
Aug 5, 2005·Environmental Health Perspectives·Shanna H SwanUNKNOWN Study for Future Families Research Team
Sep 24, 2005·Toxicological Sciences : an Official Journal of the Society of Toxicology·Shin-Ichiro SugiyamaKiyoshi Yamauchi
Nov 1, 2005·Molecular and Cellular Endocrinology·Ekaterina BreousUlrich Loos
Dec 20, 2005·Early Human Development·Victorine B de Graaf-Peters, Mijna Hadders-Algra
Feb 20, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·C A Wilson, D C Davies
Jun 30, 2007·Journal of Child and Adolescent Psychiatric Nursing : Official Publication of the Association of Child and Adolescent Psychiatric Nurses, Inc·Mary K BaileyAnd Marion Hemstrom-Krainess
Jul 20, 2007·Environmental Health Perspectives·John D MeekerRuss Hauser
Sep 19, 2007·Best Practice & Research. Clinical Endocrinology & Metabolism·Dick F Swaab
Feb 2, 2008·Current Problems in Pediatric and Adolescent Health Care·Sheela Sathyanarayana
Apr 16, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·Kembra L HowdeshellLeon Earl Gray
Apr 30, 2009·Seminars in Reproductive Medicine·Charles E RoselliPatricia D Hurn
Nov 19, 2009·International Journal of Andrology·S H SwanB Weiss
Jan 29, 2010·Environmental Health Perspectives·Stephanie M EngelMary S Wolff
Jul 14, 2010·Environmental Health Perspectives·Malene BoasKatharina M Main
Oct 29, 2010·Journal of Anatomy·Gregory A LodygenskyPetra S Hüppi
Dec 25, 2010·Neurotoxicology·Amir MiodovnikMary S Wolff
Jan 15, 2011·Environmental Health Perspectives·Tracey J WoodruffJackie M Schwartz
Mar 29, 2011·Environmental Research·Aditi RoyRebecca J Stoltzfus
Mar 29, 2011·Environment International·Lidia CasasUNKNOWN INMA Project
Jun 24, 2011·International Journal of Andrology·Y SuzukiH Shiraishi
Mar 9, 2012·Environmental Health Perspectives·Morten Søndergaard JensenBo A G Jönsson
Jul 5, 2012·Progress in Neuro-psychopharmacology & Biological Psychiatry·Shingo MatsudaEiji Shimizu
Dec 13, 2012·Psychological Bulletin·Tara M Chaplin, Amelia Aldao

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Citations

Jan 9, 2021·Environment International·Drew B DaySheela Sathyanarayana
Apr 4, 2021·International Journal of Environmental Research and Public Health·Machiko Minatoya, Reiko Kishi
May 1, 2021·International Journal of Molecular Sciences·Laura LucaccioniLorenzo Iughetti
Aug 22, 2021·Environmental Research·Viviana RamírezAna Rivas

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