Prenatal detection of heart defects in a non-selected population of 30,149 fetuses--detection rates and outcome

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
E TegnanderS H Eik-Nes

Abstract

To evaluate the detection rate of congenital heart defects (CHD) in a non-selected population and to follow outcome after diagnosis. All 30,149 fetuses/newborns that were scheduled to deliver at our hospital between February 1991 and December 2001 were registered prospectively. Of these, 29,460 (98%) fetuses had a prenatal ultrasound scan at our center. The routine fetal examination at approximately 18 weeks' gestation included the four-chamber view and the great arteries of the fetal heart. The follow-up period was 2-13 years. Of 97 major CHDs, 55 (57%) were detected prenatally, 16% (9/55) prior to, 66% (36/55) at and 18% (10/55) after the routine scan. Forty-four percent (19/43) of the isolated CHDs, 67% (36/54) of those with associated malformations and 48% (11/23) of the isolated ductal-dependent CHDs were detected. Thirty-eight percent (37/97) had an abnormal karyotype. Of the 55 major CHDs detected, 44% (24) of the pregnancies with lethal/serious fetal malformations were terminated, 15% (8) died in utero, 42% (23) were born alive and 27% (15) were still alive after 2 years. Of the 42 CHDs detected postnatally, 2% (1) were terminated for other reasons, 98% (41) were born alive and 81% (34) were still alive after 2 years. P...Continue Reading

References

May 11, 1992·American Journal of Obstetrics and Gynecology·B BromleyB R Benacerraf
Mar 1, 1992·British Journal of Obstetrics and Gynaecology·G K Sharland, L D Allan
Jun 28, 1986·British Medical Journal·L D AllanM J Tynan
Feb 1, 1988·American Journal of Obstetrics and Gynecology·J A CopelC S Kleinman
Aug 1, 1988·American Journal of Obstetrics and Gynecology·D C CrawfordL D Allan
Aug 1, 1988·American Journal of Obstetrics and Gynecology·K A BergJ A Boughman
Mar 1, 1971·Circulation·S C MitchellH W Berendes
Jun 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E TegnanderD T Linker
Oct 1, 1994·The Annals of Thoracic Surgery·M L Jacobs, W I Norwood
Jul 1, 1994·Archives of Disease in Childhood·M Abu-HarbC Wren
May 1, 1994·Journal of the American College of Cardiology·L D AllanN L Fagg
Nov 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M A RusticoG Mandruzzato
Dec 1, 1996·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S R Goldstein
Mar 1, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S J YooA Kim
Dec 31, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J A HyettK H Nicolaides
Jun 13, 1998·American Journal of Perinatology·R S EapenW H Franklin
Sep 22, 1998·Prenatal Diagnosis·E HafnerK Philipp
Mar 18, 1999·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C V IsaksenS H Torp
May 14, 1999·Cardiology in the Young·A MebergS J Sörland
May 18, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·S AinsworthC Wren
Sep 24, 1999·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P SchwärzlerY Ville
Jan 5, 2000·Pediatrics International : Official Journal of the Japan Pediatric Society·Y MaenoH Kato
Mar 30, 2001·The Journal of Thoracic and Cardiovascular Surgery·P M VerheijenG B Bennink
Jun 2, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E GarneUNKNOWN Euroscan Group
May 25, 2002·Scandinavian Cardiovascular Journal : SCJ·Talvikki BoldtMarianne Eronen
Jul 9, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M C HaakJ M G Van Vugt
Aug 10, 2002·Pediatric Cardiology·D H Brick, L D Allan
Sep 19, 2002·Journal of Perinatal Medicine·Andrew SandsFrank Casey
Jan 16, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S F WongC Ward
Jan 16, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R Chaoui, R McEwing

❮ Previous
Next ❯

Citations

May 6, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Maria T Grønning DaleMargarete E Vollrath
Jun 25, 2013·Journal of Pediatric Psychology·Maria T G DaleMargarete E Vollrath
Apr 15, 2010·Journal of Tropical Pediatrics·Ram NampoothiriVijayakumar Krishnapillai
Jun 7, 2012·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Amanda J Hines
Mar 21, 2009·Current Opinion in Obstetrics & Gynecology·Laurent J Salomon, Yves Ville
Feb 22, 2012·Clinical Obstetrics and Gynecology·Luís F GonçalvesWesley Lee
Dec 23, 2008·Journal of Perinatal Medicine·Dennis WoodUNKNOWN World Association of Perinatal Medicine Ultrasonography Working Group
Feb 13, 2014·BMC Public Health·Li WuQingguo Zhao
Jan 31, 2014·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Kjersti Jystad PostmyrAlf Meberg
Jun 12, 2012·ISRN Obstetrics and Gynecology·Torbjørn Moe EggebøChristian Lycke Ellingsen
Jun 4, 2014·BMC Medical Imaging·Eric HildebrandBirgitta Janerot-Sjoberg
Aug 28, 2014·Cardiology in the Young·Sally-Ann B Clur, Caterina M Bilardo
Feb 5, 2013·Indian Journal of Pediatrics·Saurabh Kumar Gupta, Shyam S Kothari
Apr 25, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·José A SainzRogelio Garrido Teruel
Mar 5, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Antonio Alberto ZuppaCostantino Romagnoli
Nov 2, 2013·Seminars in Perinatology·Lyndon M Hill
Jun 1, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Carla RamalhoNuno Montenegro
Apr 5, 2011·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·R BonnefoyA Chantepie
Sep 22, 2011·Obstetrics and Gynecology·Alexander M FriedmanNadav Schwartz
May 25, 2011·Obstetrics and Gynecology·Susana PereiraKypros H Nicolaides
Mar 28, 2009·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·I DurandC Marguet
May 22, 2008·The Journal of Pediatrics·Alf MebergInger Elisabeth Silberg
Oct 13, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G OggèT Todros
Aug 2, 2008·Acta Paediatrica·Alf Meberg
Nov 28, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D PaladiniC Nappi
Apr 17, 2007·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Angela E LinIan Adatia
Jun 15, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C M BilardoE K Bijlsma
Sep 6, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·K OfferdalS H Eik-Nes
Apr 3, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·K OfferdalS H Eik-Nes
May 28, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L B UittenbogaardJ M G Van Vugt
Aug 28, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S F WongF Y Chan
Jun 1, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E Tegnander, S H Eik-Nes
Dec 26, 2006·Acta Paediatrica·Annamari NikkiläBengt Källén
Mar 31, 2012·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·V JowettH M Gardiner
Jan 4, 2012·Congenital Heart Disease·Abdulrahman Al-MesnedMaha Sayed
Sep 15, 2011·Prenatal Diagnosis·S A B ClurC M Bilardo
Sep 16, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L J SalomonUNKNOWN ISUOG Clinical Standards Committee
Apr 13, 2012·Prenatal Diagnosis·S A ClurC M Bilardo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.