Prenatal diagnosis and clinical significance of hypoplastic umbilical artery

Prenatal Diagnosis
B Petrikovsky, E Schneider

Abstract

This study reports the maternal, fetal, and neonatal outcomes in cases with hypoplastic umbilical artery. The sonographic finding of a three-vessel umbilical cord showing an artery-to-artery diameter difference of more than 50 per cent was defined as hypoplastic umbilical artery. All fetuses diagnosed with hypoplastic umbilical artery underwent genetic amniocentesis and ultrasound. Fetal, maternal, and neonatal outcomes were analysed. Twelve fetuses with hypoplastic umbilical artery were detected over a 6-year period (1989-1995). Associated abnormalities included trisomy 18 (one case), polyhydramnios (three cases), congenital heart disease (one case), and fetal growth restriction (two cases). Maternal diabetes was detected in four cases. The pregnancy was terminated in one case; one neonate with severe fetal growth restriction expired; and one survived with congenital heart disease. The presence of hypoplastic umbilical artery was associated with increased perinatal morbidity and congenital abnormalities. Diabetes was frequently detected. Fetal surveillance and echocardiography are indicated in cases of hypoplastic umbilical artery.

References

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Citations

Jun 26, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A Weissman, A Drugan
Oct 20, 2005·Acta Obstetricia Et Gynecologica Scandinavica·Cristina Martínez-PayoEnrique Iglesias Goy
Nov 25, 1998·Prenatal Diagnosis·W SepulvedaL F Gonçalves
Apr 1, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·W SepulvedaM J Monckeberg
Mar 22, 2003·Current Urology Reports·Christopher W Johnson, Steven Y Tennenbaum
Jan 14, 2011·Proteomics·Nisha VermaSimone Schmitz-Spanke
Oct 16, 2012·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F GámezL Ortiz-Quintana
Jul 10, 2013·Journal of Magnetic Resonance Imaging : JMRI·Coral BravoLuis Ortiz-Quintana

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