PMID: 7724135May 1, 1995Paper

Prenatal diagnosis and therapy for a fetal hepatic vascular malformation

Obstetrics and Gynecology
A A MejidesM C Nicholas

Abstract

Congenital hepatic arteriovenous malformations complicated by high-output heart failure and hematologic derangements are associated with up to 90% mortality. Prenatal diagnosis alerts the pediatrician to the need for early neonatal intervention. A fetal hepatic arteriovenous malformation with associated high-output cardiac failure was diagnosed at 29 weeks' gestation using real-time and color flow Doppler sonography. Hydrocortisone injected directly into the umbilical vein and the amniotic sac resulted in appreciable improvement in hemodynamic and hematologic indices. The pregnancy ended in a preterm delivery at 31 weeks with no evidence of heart failure at birth. The compromised preterm fetus with a hepatic arteriovenous malformation can be treated in utero, avoiding early emergency delivery.

References

Nov 1, 1991·Journal of Pediatric Surgery·F I LuksH Blanchard
Feb 1, 1990·European Journal of Pediatrics·D GozalM Jaffe

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Citations

Oct 20, 2010·Pediatric Surgery International·Kokila Lakhoo, Helen Sowerbutts
Sep 8, 2000·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J J TsengE S Ho
Feb 13, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J HartungR Bollmann
May 2, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·U GembruchU Germer
May 2, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·K-S HelingR Bollmann
Aug 6, 1999·Journal of Pediatric Gastroenterology and Nutrition·T LamireauN Grenier
Jan 18, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Paula J WoodwardKelly K Koeller
Oct 20, 2010·Early Human Development·Erica Makin, Mark Davenport
Jan 9, 2007·Journal of Pediatric Surgery·Emily R Christison-LagaySteven J Fishman
Sep 26, 2006·Annales de chirurgie plastique et esthétique·L-M BoonG Verellen
Apr 3, 2009·Prenatal Diagnosis·Elena SinkovskayaAlfred Abuhamad
Dec 11, 2014·Pediatric Radiology·Maria A Calvo-GarciaTal Laor
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Jan 26, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D KamilC Berg
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