Prenatal diagnosis of biliary atresia: A case series

Early Human Development
O ShenE Granot

Abstract

Biliary atresia is a progressive disease presenting with jaundice, and is the most common indication for liver transplantation in the pediatric population. Prenatal series have yielded conflicting results concerning a possible association between BA and prenatal nonvisualization of the gallbladder. This retrospective case series was performed to assess the association between biliary atresia, prenatal nonvisualization of the gallbladder and other sonographic signs. We identified biliary atresia patients who underwent a Kasai procedure by a single pediatric surgeon and/or follow up by a single pediatric gastroenterologist. Axial plane images and/or video recordings were scrutinized for sonographic signs of biliary atresia on the second trimester anomaly scan. Proportion of biliary atresia cases with prenatal sonographic signs. Twenty five charts of children with biliary and high quality prenatal images were retrieved. 6/25 (24%) of cases analyzed had prenatal nonvisualization of the gallbladder or a small gallbladder on the prenatal scan. Two cases had biliary atresia splenic malformation syndrome. None of the cases had additional sonographic markers of biliary atresia. Our study suggests that in addition to the well-established...Continue Reading

Citations

Apr 1, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jorge A BezerraRonald J Sokol
Jan 22, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·John-Paul BerauerUNKNOWN Childhood Liver Disease Research Network (ChiLDReN)
Jul 25, 2019·Journal of Pediatric Gastroenterology and Nutrition·Krupa R MysoreSanjiv Harpavat
Feb 28, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E Di PasquoY Ville
Feb 8, 2019·Journal of Clinical Ultrasound : JCU·Ourania KoukouraThemistoklis Dagklis
Nov 20, 2019·The Indian Journal of Radiology & Imaging·Prateek Agarwal, Rajesh Kumar Agarwal
Sep 3, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Miao HeLihe Zhang
Aug 5, 2021·Ultrasonography·Bernadette Wambui Muthee, Heather J Bray

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