Prenatal diagnosis of congenital heart disease: trends in pregnancy termination rate, and perinatal and 1-year infant mortalities in Korea between 1994 and 2005

The Journal of Obstetrics and Gynaecology Research
Ji Eun LeeJong-Hwa Kim

Abstract

To determine the pregnancy termination rate, and perinatal and 1-year infant mortality rates following prenatally-detected congenital heart disease (CHD) and trends over an 11-year period. Between 1994 and 2005, 1603 gravidas underwent fetal echocardiography in our institution, in which 378 fetuses were diagnosed with CHD. The study period was divided into the following three groups for time-trend analysis: 1994-1997, 1998-2001, and 2002-2005. Data regarding gestational age at diagnosis and delivery, the presence of extracardiac or chromosomal abnormalities, pregnancy termination rate, and perinatal and 1-year mortalities were collected by review of medical records and telephone interviews. Among 378 fetuses with a prenatally-detected CHD, complete perinatal and infant outcomes were available for 336 fetuses (88.9%). There was a gradual increase in prenatally-detected CHD by fetal echocardiography during the study period (1994-1997, 10.3%; 1998-2001, 17.3%; and 2002-2005, 24.3%). The mean gestational ages at diagnosis and delivery were 27.2 +/- 5.6 and 37.8 +/- 2.9 weeks, respectively. Overall, the pregnancy termination rate in this study population was 20.2% and the perinatal and 1-year infant mortality rates were 6.3% and 9.7...Continue Reading

References

Jun 1, 1992·The American Journal of Cardiology·J F SmytheC S Kleinman
Mar 1, 1991·Archives of Disease in Childhood·G K SharlandL D Allan
Jul 1, 1987·American Journal of Diseases of Children·H H KramerM Bourgeois
Sep 15, 1987·The American Journal of Cardiology·A R NussbaumR L Lebowitz
Jan 1, 1985·American Journal of Epidemiology·C FerenczJ W Downing
May 1, 1995·Pediatric Cardiology·J I Hoffman
May 1, 1994·Journal of the American College of Cardiology·L D AllanN L Fagg
Jun 1, 1993·Journal of the American College of Cardiology·D E FixlerC W Eifler
Dec 31, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J A CopelC S Kleinman
Apr 3, 1999·International Journal of Cardiology·V Grech, M Gatt
Jun 2, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E GarneUNKNOWN Euroscan Group
Sep 29, 2001·Obstetrics and Gynecology·K LeeR L Mittendorf
May 1, 2002·Prenatal Diagnosis·Alan H FriedmanJoshua A Copel
May 25, 2002·Scandinavian Cardiovascular Journal : SCJ·Talvikki BoldtMarianne Eronen
Jun 27, 2002·Journal of the American College of Cardiology·Julien I E Hoffman, Samuel Kaplan
Jan 1, 1991·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L D AllanD J Maxwell
Jun 17, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S LeviUNKNOWN Eurofetus study group
Jul 3, 2003·The Journal of Pediatrics·Giuliano BosiUNKNOWN IMER Working Party
Dec 14, 2004·American Journal of Obstetrics and Gynecology·Jay W MooreRebecca Berry
May 22, 2007·Clinical Obstetrics and Gynecology·Uma M Reddy, Ronald J Wapner
Jun 26, 2007·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Sheng-Mou HsiaoFon-Jou Hsieh

❮ Previous
Next ❯

Citations

Feb 14, 2014·Cardiology Research and Practice·Luciane Alves RochaAntonio Fernandes Moron
May 16, 2014·Pediatric Cardiology·Alexander EgbeShubhika Srivastava
Mar 13, 2014·Congenital Heart Disease·Alexander EgbeShubhika Srivastava
Apr 24, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B J HollandC R Woods
Sep 11, 2014·PloS One·Rachel L KnowlesUNKNOWN UKCSCHD (UK Collaborative Study of Congenital Heart Defects) collaborators
Jun 22, 2019·Journal of Korean Medical Science·Susan Taejung KimCheong Rae Roh
Aug 11, 2017·The Korean Journal of Thoracic and Cardiovascular Surgery·Yoon Sang ChungJoonhwa Hong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.