Prenatal diagnosis of congenital heart disease: impact of mode of delivery on neonatal outcome

Prenatal Diagnosis
Luca U TrentoMark S Sklansky

Abstract

We sought to evaluate the impact of mode of delivery (MOD) on early outcome for neonates diagnosed prenatally with major forms of congenital heart disease (CHD). We retrospectively studied infants admitted, over a 2-year period, to a single institution for cardiac intervention. Infants were grouped on the basis of timing of diagnosis (prenatal/postnatal) and MOD--planned (induced labor or planned cesarean delivery) versus spontaneous labor. Multivariate logistic regression was used to evaluate independent predictors for MOD and early outcomes. Of 329 patients, 45% received a prenatal diagnosis of CHD. A prenatal diagnosis of CHD increased the likelihood for planned delivery [odds ratio (OR) 2.6, 95% confidence interval (CI) 1.6 to 4.5, p < 0.001]. Newborns prenatally diagnosed with CHD were more likely to have been delivered between 8 am and 6 pm, Monday through Friday (OR 2.3, 95% CI 1.1 to 4.8, p = 0.019). However, MOD had no statistical impact on Apgar score, duration of pre-operative intubation, and survival to surgery or to discharge. The Risk Adjustment for Congenital Heart Surgery 1 surgical mortality score was the only independent predictor of hospital mortality. In our experience, although a prenatal diagnosis of CHD d...Continue Reading

References

Apr 1, 1983·Archives of Disease in Childhood·G FaxeliusL Irestedt
Aug 1, 1995·Archives of Pediatrics & Adolescent Medicine·D J AnnibaleW M Southgate
Dec 31, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J A CopelC S Kleinman
May 27, 1999·Pediatric Pulmonology·S LeeA D Milner
Mar 10, 2001·Circulation·Wayne TworetzkyNorman H Silverman
Mar 10, 2001·Obstetrics and Gynecology·E M LevineC M Strom
Dec 4, 2001·American Journal of Perinatology·V MirlesseF Daffos
Jan 10, 2002·The Journal of Thoracic and Cardiovascular Surgery·Kathy J JenkinsLisa I Iezzoni
Apr 3, 2004·Pediatrics·Jodi M BartlettJane W Newburger
Apr 4, 2006·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ariel ManyShaul Dollberg
Nov 6, 2007·BMJ : British Medical Journal·José VillarWorld Health Organization 2005 Global Survey on Maternal and Perinatal Health Research Group
Nov 22, 2008·European Journal of Obstetrics, Gynecology, and Reproductive Biology·M J RaboissonA Bozio
Jan 9, 2009·The New England Journal of Medicine·Alan T N TitaEunice Kennedy Shriver NICHD Maternal-Fetal Medicine Units Network
Apr 28, 2009·The Journal of Pediatrics·Mark K FriedbergLisa K Hornberger
Jun 2, 2009·American Journal of Obstetrics and Gynecology·Keiko UedaIsao Shiraishi
Jun 24, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Mark S SklanskyRuey-Kang R Chang
Dec 25, 2009·Circulation. Cardiovascular Quality and Outcomes·Vasum PeirisDavid W Brown
Feb 19, 2010·Pediatric Cardiology·Allison LeveyIsmee A Williams

Citations

May 31, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·C A WalshF M McAuliffe
Feb 16, 2016·Clinics in Perinatology·Laura SanapoMary T Donofrio
Apr 24, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B J HollandC R Woods
Apr 1, 2015·Seminars in Fetal & Neonatal Medicine·Jay D PruetzDavid A Miller
Jun 8, 2013·Seminars in Fetal & Neonatal Medicine·Alice WielandnerVanessa Berger-Kulemann
Mar 17, 2015·Frontiers in Pediatrics·Antonio Francesco Corno
Nov 29, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Takekazu MiyoshiTomoaki Ikeda
Jun 5, 2017·American Journal of Obstetrics and Gynecology·Laura I ParikhUma M Reddy
Mar 17, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Cathy LiuSailesh Kumar
Aug 30, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mehmet Resit AsogluOzhan M Turan
Sep 5, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mamatha GowdaLaxmi Godipelli
Oct 16, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·April D AdamsSara N Iqbal

Related Concepts

Congenital Heart Defects
Infant, Small for Gestational Age
Antenatal Screening Procedures
Retrospective Studies
Obstetric Delivery
Cesarean Section
Congenital Heart Defects
Intubation
Retrospective Studies
Drug Delivery Systems

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