Prenatal diagnosis of conotruncal malformations: diagnostic accuracy, outcome, chromosomal abnormalities, and extracardiac anomalies

American Journal of Perinatology
Shanthi SivanandamCharles S Kleinman

Abstract

The purpose of this study was to determine whether continuing experience in prenatal diagnosis of conotruncal malformations (CTMs) has resulted in improved diagnostic accuracy and outcome. Previous reports have demonstrated particular difficulty with ascertainment of the spatial relationship of the great arteries in patients with CTM. The prognosis for fetuses with CTM was poor. Medical records of 113 consecutive fetuses in whom a CTM (tetralogy of Fallot [TOF], double-outlet right ventricle [DORV], type B aortic arch interruption, transposition of the great arteries [TGA], and persistent truncus arteriosus [TA]) was diagnosed antenatally between 1994 and 2003 were reviewed. The diagnosis of the 91 fetuses with CTM included TOF (n = 32), TGA (n = 29), DORV (n = 22), and TA (n = 8). The great arterial spatial relationship was diagnosed accurately in 84 of the 91 (92%) live-born infants. In the other seven infants with DORV, the great arterial spatial relationship was identified inaccurately. The overall survival to 30 days was 85 of 91 (93%). Twenty-three of 91 (25%) patients had extracardiac anomalies. Genetic diagnosis (amniocentesis) was obtained in 63 of 94 patients; 11 (17%) had chromosomal abnormalities. Maternal glucose t...Continue Reading

Citations

Dec 17, 2008·Pediatric Cardiology·Javier H GonzalezAnthony M Hlavacek
Apr 27, 2012·Annals of Biomedical Engineering·Koonal N BharadwajJonathan T Butcher
Feb 2, 2011·Advanced Drug Delivery Reviews·Jonathan T ButcherLaura A Hockaday
Jun 2, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A GalindoO Nieto
Dec 24, 2008·Journal of Clinical Ultrasound : JCU·Nobuhiro HidakaNorio Wake
Mar 6, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J M MartínezE Gratacós
Mar 16, 2012·Prenatal Diagnosis·Jaime L NatoliJanice G Edwards
Oct 9, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Yi XiongTze Kin Lau
May 28, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Phudit JatavanTheera Tongsong
Mar 3, 2017·Cardiology in the Young·UNKNOWN Authors/Task Force Members:Pascal R Vouhé
Apr 22, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Christopher T LamPirooz Eghtesady
May 13, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Amir ZayeghBennett Sheridan
Oct 23, 2010·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jimmy EspinozaSimcha Yagel
Jan 13, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·George E SarrisPascal R Vouhé
Aug 24, 2007·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jimmy EspinozaSonia S Hassan
Apr 1, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Lami YeoRoberto Romero
Mar 14, 2007·Current Opinion in Obstetrics & Gynecology

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