Prenatal Diagnosis of Hydro(metro)colpos: A Series of 20 Cases

Fetal Diagnosis and Therapy
Michael R MallmannU Gembruch

Abstract

Hydrocolpos and hydrometrocolpos are rare malformations caused by accumulation of secretion due to congenital obstruction of the vagina. Hydro(metro)colpos may be isolated or can be combined with other malformations as part of a syndromic disorder. We report on a series of 20 cases with hydro(metro)colpos diagnosed prenatally, delineate the differential diagnoses, and illustrate the spectrum of associated malformations. This was a retrospective study involving 20 fetuses with hydro(metro)colpos at two large tertiary referral centers in Germany over an 18-year period (2000-2017). The median diagnosis was made at 30+4 weeks of gestation, the earliest at 20+6 weeks, the latest at 37+2 weeks. All 20 fetuses presented with the typical cystic structure behind the fetal bladder. Additional malformations included urogenital malformations, hexadactyly, and heart defects. Postnatal follow-up revealed that hydro(metro)colpos was associated with anorectal malformation in 11/20 fetuses, McKusick-Kaufman syndrome or Bardet-Biedl syndrome in 4/20 fe tuses, Mayer-Rokitansky-Küster-Hauser syndrome in 3/20 fetuses, and Herlyn-Werner-Wunderlich syndrome in 1/20. In 1 fetus pressure from an intraabdominal teratoma resulted in prenatal hydro(metro)...Continue Reading

References

Mar 1, 1997·American Journal of Obstetrics and Gynecology·O Geifman-HoltzmanM Holmes
Jun 1, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A O OdiboW A Campbell
Dec 31, 1997·American Journal of Medical Genetics·J P Fryns
Apr 29, 1998·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M Respondek-LiberskaE Czichos
May 30, 2001·Current Opinion in Genetics & Development·V C SheffieldE M Stone
Sep 1, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A GeipelU Gembruch
Mar 19, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C BergU Gembruch
Sep 27, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S HayashiM Natori
Mar 9, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Canan AygunSükrü Küçüködük
Mar 16, 2007·Orphanet Journal of Rare Diseases·Karine MorcelDaniel Guerrier
Jan 6, 2009·Fetal Diagnosis and Therapy·R Douglas WilsonN Scott Adzick
Jul 14, 2010·Journal of Pediatric Surgery·Andrea BischoffAlberto Peña
Nov 4, 2010·European Journal of Medical Genetics·Elise SchaeferHélène Dollfus
Jan 5, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·S Boopathy VijayaraghavanPurushothaman Suganyadevi
Aug 22, 2012·Reproductive Biology and Endocrinology : RB&E·Patricia G OppeltAndreas Mueller
Nov 22, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·W AbdennadherF Muller
May 11, 2016·Fetal Diagnosis and Therapy·Michael Rudolf MallmannUlrich Gembruch
Oct 21, 2016·Archives of Gynecology and Obstetrics·R StadiéC Berg
Nov 9, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Karina KapczukWitold Kędzia

❮ Previous
Next ❯

Citations

Apr 20, 2019·Frontiers in Pediatrics·Beatiz Bañuelos MarcoAnja Lingnau
Jan 24, 2020·Sudanese Journal of Paediatrics·Nader Mutwakel OsmanHiba Asim Mustafa Elamin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
K TaoriV Patil
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Yinon GilboaSharon Perlman
Taiwanese Journal of Obstetrics & Gynecology
Hsing-Fen TsaiFong-Ming Chang
© 2022 Meta ULC. All rights reserved