Prenatal diagnosis of nuchal cystic hygroma

The British Journal of Radiology
A M MacLeod, J M McHugo


Twenty-seven cases of nuchal cystic hygroma were diagnosed prenatally over a 5-year period at the Birmingham Maternity Hospital. Karyotypes were obtained in 20 cases, of which 14 (70%) were abnormal. Two-thirds of these represented various trisomy syndromes in contrast to other series where cases of Turner's syndrome have predominated. Twenty pregnancies were terminated. There was one intra-uterine death and two neonatal deaths. Hydrops was present in 15 cases, none of which survived to term. Associated structural abnormalities, mainly skeletal, renal and cardiac, were present in 18 cases. There were four long-term survivors with good quality of life, including both normal and abnormal karyotypes. In utero regression of the hygroma was documented in five cases, total in three and subtotal in two cases born with residual neck webbing.


May 1, 1990·Journal of Clinical Ultrasound : JCU·S Rottem, M Bronshtein
Feb 1, 1989·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·M B MackenM J Vincer
Jun 1, 1989·Obstetrical & Gynecological Survey·M M CohenK J Blakemore
Aug 1, 1989·AJR. American Journal of Roentgenology·B M DistellJ D Bowie
May 1, 1988·Prenatal Diagnosis·B N ChodirkerC R Greenberg
Feb 1, 1986·American Journal of Obstetrics and Gynecology·A S GardenH A Gardner
Oct 1, 1983·British Medical Bulletin·S Campbell, J M Pearce
Jun 1, 1984·The Journal of Laryngology and Otology·P J EmeryJ N Evans
Oct 6, 1983·The New England Journal of Medicine·F A ChervenakM J Mahoney


Jan 1, 1997·European Journal of Obstetrics, Gynecology, and Reproductive Biology·P DescampsG Body
Dec 23, 2011·ISRN Obstetrics and Gynecology·J J P M PietersA P T Smits
Jun 26, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Min ChenMary Hoi Yin Tang
Dec 16, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Hüseyin Çağlayan ÖzcanTanyeli Güneyligil Kazaz
Aug 28, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E SurerusL D Allan
Mar 2, 2006·Obstetrics and Gynecology·Francisca S MolinaKypros H Nicolaides

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Related Papers

The Medical Journal of Australia
R A Jones
The New England Journal of Medicine
F A ChervenakM J Mahoney
American Journal of Obstetrics and Gynecology
A S GardenH A Gardner
American Journal of Obstetrics and Gynecology
M P JohnsonM I Evans
© 2021 Meta ULC. All rights reserved