PMID: 9633572Jun 20, 1998Paper

Prenatal diagnosis. Therapeutic implications

The Urologic Clinics of North America
P P Reddy, J Mandell

Abstract

Prenatal diagnosis of structural anomalies provides the opportunity to influence the postnatal outcome. The greatest value of antenatal screening is, in fact, the awareness of the urogenital abnormalities, such as presumed UPJ obstruction, so that appropriate investigation and treatment can be offered immediately after birth and before permanent damage occurs owing to obstruction or infection. Crombleholme and coworkers reported that prenatal consultation impacted favorably on outcomes by preventing early termination of pregnancy owing to misconceptions about the existing condition. It also permitted delivery of complex cases in a tertiary care setting, thereby preventing a delay in postnatal management. A systematic approach to the infant in the prenatal and postnatal periods is important. The natural history of prenatally detected hydronephrosis continues to be defined, and there is no ideal test to predict the outcome of UPJ obstruction. Several investigators are evaluating various markers in urine that may help to identify fetuses who require early postnatal intervention. More complete understanding regarding the natural history of unilateral pediatric UPJ obstruction and its response to surgery will not be available until ...Continue Reading

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Citations

Jun 24, 2005·Indian Journal of Pediatrics·Prema Menon, K L N Rao
Feb 15, 2014·Best Practice & Research. Clinical Obstetrics & Gynaecology·Tiran DiasShanya Kumarasiri
Apr 29, 1999·Current Opinion in Obstetrics & Gynecology·M P Johnson, A L Freedman
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Sep 20, 2001·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·J P FrazierR J Yetman
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Jul 31, 2004·American Journal of Obstetrics and Gynecology·Michael W KilpatrickPetros Tsipouras
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Jul 4, 2001·The Journal of Urology·M SouliéP Plante
Aug 24, 1999·The Journal of Urology·I M McAleer, G W Kaplan
Mar 19, 2019·International Journal of Urology : Official Journal of the Japanese Urological Association·Eriko KohataKazunari Kaneko
Jul 13, 2004·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Helmut SchoellnastMichael Riccabona
Nov 9, 2007·Seminars in Fetal & Neonatal Medicine·Pierre-Yves Mure, Pierre Mouriquand

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