Prenatal exposure to acetaminophen and asthma in children.

Obstetrics and Gynecology
Elizabeth M KangMichael B Bracken

Abstract

To estimate whether prenatal exposure to acetaminophen is associated with risk of diagnosed asthma and asthma symptoms in children. The authors prospectively followed 1,505 pregnant women and their children until 6 years (+/-3 months) of life. Acetaminophen use in the first and third trimesters of pregnancy was assessed before 24 weeks of gestation and within 1 month of delivery, and asthma in children was assessed when the child was 6 years old. Adjusted odds ratios (aORs) were derived from logistic regression models controlling for potential confounders. Acetaminophen was used by 69% of women during pregnancy. Use of acetaminophen did not significantly increase the risk of asthma (aOR 0.76, 95% confidence interval [CI] 0.53-1.10). Acetaminophen use during both the first and the third trimester was associated with a significantly reduced risk of asthma (aOR 0.59, 95% CI 0.36-0.98). There was no evidence of a dose response, and consumption greater than 10,400 mg (32 tablets) a month did not increase risk (aOR 0.99, 95% CI 0.19-5.30). Our results suggest that acetaminophen use during pregnancy does not increase risk of asthma in children. II.

References

Dec 2, 1977·European Journal of Clinical Pharmacology·P SkjelbredP Lokken
Feb 19, 1979·European Journal of Clinical Pharmacology·P Skjelbred, P Løkken
Jan 19, 1995·The New England Journal of Medicine·F D MartinezW J Morgan
Nov 14, 1997·Anesthesia and Analgesia·J P RathmellM A Ashburn
Nov 11, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·A E VarnerR F Lemanske
Mar 18, 2000·Thorax·S O ShaheenP G Burney
Jan 10, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·S A ComhairS C Erzurum
Feb 15, 2001·The American Journal of Medicine·S Hernández-Díaz, L A García-Rodríguez
Oct 31, 2002·Thorax·S O ShaheenUNKNOWN ALSPAC Study Team
Jan 9, 2004·American Journal of Respiratory and Critical Care Medicine·R Graham BarrCarlos A Camargo
May 29, 2004·European Journal of Clinical Pharmacology·J HeadleyUNKNOWN ALSPAC Study Team
Sep 15, 2004·Journal of Epidemiology and Community Health·Catherine CohetNeil Pearce
Jan 15, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S O ShaheenUNKNOWN ALSPAC Study Team
Sep 10, 2005·American Journal of Obstetrics and Gynecology·Martha M WerlerMargaret A Honein
Mar 7, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Riece KonimanHugo P Van Bever
Jan 30, 2008·American Journal of Obstetrics and Gynecology·Cristina RebordosaJørn Olsen
Apr 11, 2008·International Journal of Epidemiology·Cristina RebordosaJørn Olsen
Sep 26, 2008·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Victoria PerskyAdela Busso
Nov 27, 2008·International Archives of Allergy and Immunology·L Garcia-MarcosJ Valverde-Molina
Feb 13, 2009·Current Allergy and Asthma Reports·Henning AllmersSwen Malte John

❮ Previous
Next ❯

Citations

Dec 31, 2010·American Journal of Epidemiology·Kari R RisnesMichael B Bracken
Oct 12, 2010·Current Opinion in Obstetrics & Gynecology·Stephen A Contag, Cheryl Bushnell
Dec 29, 2011·Clinical & Developmental Immunology·Yang-Ching ChenYungling Lee
May 10, 2013·Environmental Health : a Global Access Science Source·Ann Z Bauer, David Kriebel
Dec 18, 2015·Pharmacoepidemiology and Drug Safety·Xiaoqin LiuJiong Li
Feb 26, 2013·Journal of Reproductive Immunology·Kristin ThieleGisa Tiegs
Mar 7, 2013·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·L MoralUNKNOWN SEICAP, SENP, SEPEAP, AEPAP, CM-AEP
Dec 21, 2012·Allergologia et immunopathologia·L MoralM A Pena
Jan 26, 2013·Paediatric Respiratory Reviews·A John Henderson, Seif O Shaheen
Feb 1, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Elizabeth W TricheMichael B Bracken
Oct 5, 2010·The Journal of Allergy and Clinical Immunology·Eva SchnabelUNKNOWN LISA Study Group
Feb 23, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S EyersR Beasley
Feb 8, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C C Johnson, D R Ownby
Oct 1, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K WickensUNKNOWN New Zealand Asthma and Allergy Cohort Study Group
Jul 8, 2011·The International Journal of Pharmacy Practice·Rodney StosicIan Adams
Nov 3, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H W ChuA J Wardlaw
Jul 20, 2011·Acta Paediatrica·Emma GoksörGöran Wennergren
Feb 14, 2012·Birth Defects Research. Part A, Clinical and Molecular Teratology·Sonja A Rasmussen
Sep 16, 2014·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M WeatherallR Beasley
Feb 22, 2011·American Journal of Obstetrics and Gynecology·Sonja A RasmussenUNKNOWN Pandemic Influenza and Pregnancy Working Group
Dec 3, 2014·The Journal of Allergy and Clinical Immunology·Joanne E SordilloAugusto A Litonjua
Aug 26, 2015·PloS One·Enrica MiglioreLorenzo Richiardi
Aug 31, 2016·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Tamara Lourido-CebreiroFrancisco-Javier Gonzalez-Barcala
Oct 11, 2015·Seminars in Perinatology·Christina Chambers
Apr 21, 2011·Current Opinion in Allergy and Clinical Immunology·Luis Garcia-MarcosVirginia Perez-Fernandez
Dec 11, 2013·Current Opinion in Allergy and Clinical Immunology·Haejin Kim, Christine C Johnson
Jan 23, 2013·Maternal and Child Health Journal·Charlene H CollierJessica L Illuzzi
Nov 5, 2010·Current Opinion in Obstetrics & Gynecology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

© 2022 Meta ULC. All rights reserved