Prenatal exposure to ambient temperature variation increases the risk of common cold in children

Ecotoxicology and Environmental Safety
Chan LuQihong Deng

Abstract

Common cold is a frequent upper respiratory tract infection, but the role of ambient temperature in the infection is unclear. We investigated the role of prenatal exposure to diurnal temperature variation (DTV), the difference between the daily maximal and minimal temperatures, in the risk of common cold in children. We conducted a cohort study of 2598 preschool children in Changsha, China. Occurrence of common cold during the past year was surveyed using questionnaire. We then estimated each child's prenatal exposure to DTV during pregnancy. Multivariate logistic regression model was used to examine the association between occurrence of common cold and prenatal exposure to DTV in terms of odds ratios (OR) and 95% confidence interval (CI). About 45% children have common cold (≥3 times) during the past year. We found that common cold in children was associated with maternal DTV exposure during pregnancy, particularly during the first trimester with adjusted OR (95% CI) = 1.27 (1.10-1.46). Male and atopic children were more susceptible to the effect of DTV during pregnancy. The risk of common cold due to DTV is higher in children living in the suburban areas and the bigger houses and in those exposed to environmental tobacco smok...Continue Reading

Citations

Nov 24, 2018·Environmental Science and Pollution Research International·Yunzhao RenHao Xiang
Nov 5, 2020·Environmental Science and Pollution Research International·Guoyu ZhouYue Ba
May 2, 2021·Environmental Science and Pollution Research International·Fengliu FengHaoran Jiao
Apr 27, 2021·Pediatrics International : Official Journal of the Japan Pediatric Society·Tomohiro IshimaruYoshihisa Fujino

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