Prenatal karyotypes of fetuses conceived by intracytoplasmic sperm injection

Fertility and Sterility
Esra Aksoy JozwiakM Bahceci

Abstract

To evaluate the rate of chromosomal abnormalities in babies conceived by intracytoplasmic sperm injection (ICSI). Retrospective case-control analysis. Private IVF center. One thousand one hundred thirty-six karyotype results obtained from fetuses conceived by ICSI. Amniocentesis and prenatal karyotyping. Presence of normal and abnormal chromosomal configurations. Abnormal karyotypes were detected in 17 (1.5%) of 1,136 fetuses. Eight (0.7%) of these were from singleton and nine (0.8%) from twin pregnancies. There was no difference in the autosomal chromosome structure or the number or structure of sex chromosomes in karyotyped fetuses of singleton and twin pregnancies. However, abnormal numbers of autosomal chromosomes were more frequent in singletons (2.3%) than in twins (1.1%). There was also no difference in the frequency of chromosomal aberrations between ICSI groups in which ejaculated spermatozoa (1.9%) and testicular spermatozoa (1.5%) were used. There was no difference in the frequency of chromosomal aberrations between fetuses for whom ICSI was used because of male factors (1.8%) compared with babies for whom ICSI was also the choice of assisted fertilization method for other types of infertility factors (0.9%). Sperm s...Continue Reading

References

Dec 1, 1996·Human Reproduction·E Van AsscheI Liebaers
Nov 26, 1999·Human Reproduction·M BonduelleA Van Steirteghem
Mar 31, 2000·Human Reproduction·U B WennerholmB Källén
Oct 27, 2001·Seminars in Reproductive Medicine·J L Simpson, D J Lamb
Apr 9, 2002·American Journal of Perinatology·André Van SteirteghemPaul Devroey
Jul 9, 2002·Human Reproduction Update·A Van SteirteghemI Liebaers
Aug 2, 2002·Human Reproduction·S AnthonyA L den Ouden
Aug 16, 2003·Clinical Genetics·D G CrugerG Bruun-Petersen
Nov 7, 2003·The Journal of Urology·Jonathan P Jarow

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Citations

Apr 24, 2012·Human Reproduction Update·Anne Cathrine GjerrisAnja Pinborg
Dec 25, 2008·Molecular Cytogenetics·Serdar KasakyanMoncef Benkhalifa
Dec 14, 2011·Asian Journal of Andrology·Jane Halliday
May 19, 2009·Journal de gynécologie, obstétrique et biologie de la reproduction·G Porcu-Buisson, C Giorgetti
Dec 31, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A C GjerrisA Tabor
Dec 18, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R MaymonI Ben-Ami
Jul 13, 2005·Fertility and Sterility·Ulun Ulug, Mustafa Bahceci
Dec 15, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Gian Mario TiboniGianna Gabriella Impicciatore
Feb 13, 2019·Human Reproduction Update·Sine BerntsenAnja Pinborg
Apr 15, 2021·Reproductive Medicine and Biology·Yukiko Katagiri, Yuko Tamaki

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