Prenatal Maternal Smoking and Tourette Syndrome: A Nationwide Register Study

Child Psychiatry and Human Development
Susanna LeivonenAndre Sourander

Abstract

This is the first nationwide register-based study to examine the relationship between prenatal maternal smoking and Tourette syndrome. A total of 767 children diagnosed with Tourette syndrome were identified from the Finnish Hospital Discharge Register. Each case was matched to four controls. Information on maternal smoking during pregnancy was obtained from the Finnish Medical Birth Register. Conditional logistic regression models were used for statistical analyses. Prenatal maternal smoking was associated with Tourette syndrome when comorbid with ADHD (OR 4.0, 95 % CI 1.2-13.5, p = 0.027 for exposure during first trimester, OR 1.7, 95 % CI, 1.05-2.7, p = 0.031 for exposure for the whole pregnancy). There was no association between maternal smoking during pregnancy and Tourette syndrome without comorbid ADHD (OR 0.5, 95 % CI 0.2-1.3, p = 0.166, OR 0.9, 95 % CI 0.7-1.3, p = 0.567). Further research is needed to elucidate the mechanisms behind the association between prenatal maternal smoking and Tourette syndrome with comorbid ADHD.

References

Jan 1, 1987·Archives of General Psychiatry·J F LeckmanD J Cohen
Jul 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·S L SantangeloJ F Leckman
Nov 6, 1998·Journal of Child Psychology and Psychiatry, and Allied Disciplines·T SpencerD Geller
Sep 6, 2000·Developmental Medicine and Child Neurology·R D FreemanP Sandor
Jun 1, 2001·American Journal of Epidemiology·L J EnglandW H Hannon
Jul 3, 2002·Epidemiology·Christina M HultmanSven Cnattingius
Aug 24, 2004·European Child & Adolescent Psychiatry·Christopher GillbergLena Niklasson
Aug 3, 2005·Pediatrics·Karen Markussen LinnetTine Brink Henriksen
Jun 3, 2006·The American Journal of Psychiatry·Carol A MathewsVictor I Reus
Dec 13, 2006·Biological Psychiatry·Rosalind J NeumanRichard D Todd
Apr 19, 2007·Paediatric and Perinatal Epidemiology·Guglielmina FantuzziSalvatore Sciacca
Sep 5, 2007·European Child & Adolescent Psychiatry·Kerstin J PlessenBradley S Peterson
Nov 22, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Susan L SmalleyMarjo-Riitta Järvelin
Mar 25, 2008·Biological Psychiatry·Marco A GradosUNKNOWN Tourette Syndrome Association International Consortium for Genetics
Sep 1, 2007·Current Neuropharmacology·R Wickström
Mar 27, 2009·Journal of Developmental and Behavioral Pediatrics : JDBP·Tamara PringsheimPaul O'Connor
Oct 13, 2009·The Journal of Pediatrics·Mikael EkbladUNKNOWN PIPARI Study Group
Nov 20, 2009·Pharmacopsychiatry·S Ferrea, G Winterer
Jan 30, 2010·Journal of Developmental and Behavioral Pediatrics : JDBP·Netty G P Bos-VenemanPieter J Hoekstra
Feb 24, 2010·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Frank Lindblad, Anders Hjern
Jun 30, 2010·Acta Obstetricia Et Gynecologica Scandinavica·Prakesh S Shah, UNKNOWN Knowledge Synthesis Group on Determinants of LBW/PT births
Aug 6, 2010·The American Journal of Psychiatry·Paul LichtensteinHenrik Anckarsäter
Aug 25, 2010·Journal of the American Academy of Child and Adolescent Psychiatry·Joel NiggS Alexandra Burt
Mar 26, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Andrea E CavannaMary M Robertson
May 11, 2011·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Julia A O'RourkeDavid L Pauls
Dec 20, 2011·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Margaret H Bublitz, Laura R Stroud
Dec 28, 2011·Biological Psychiatry·Anne HalmøyJan Haavik
Feb 9, 2012·Nature Reviews. Rheumatology·Theodoros DimitroulasGeorge D Kitas
Jul 5, 2012·Pediatric Neurology·Tristan KnightTamara Pringsheim
Aug 18, 2012·Scandinavian Journal of Public Health·Reijo Sund
Sep 12, 2012·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Anita ThaparKate Langley
Oct 25, 2012·Neuroscience and Biobehavioral Reviews·Pieter J HoekstraDavide Martino
Apr 12, 2013·Paediatric and Perinatal Epidemiology·Phuong Lien TranAndre Sourander
Sep 13, 2013·European Journal of Public Health·Mikael EkbladLiisa Lehtonen
Oct 15, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S RodgersV Ajdacic-Gross
Nov 23, 2013·The British Journal of Psychiatry : the Journal of Mental Science·Carol A MathewsYoav Ben-Shlomo
Feb 1, 2014·BMC Pregnancy and Childbirth·Ting-Kuang ChaoTamara Pringsheim
May 7, 2014·European Child & Adolescent Psychiatry·Hjördis O AtladottirErik T Parner

❮ Previous
Next ❯

Citations

Aug 28, 2016·Journal of the American Academy of Child and Adolescent Psychiatry·Heidi A BrowneDorothy E Grice
Dec 9, 2017·F1000Research·Kevin J Black
May 10, 2016·F1000Research·Kevin J BlackBradley L Schlaggar
Sep 30, 2019·International Ophthalmology·Lin ChenQing Liu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.