Prenatal parental depression and preterm birth: a national cohort study

BJOG : an International Journal of Obstetrics and Gynaecology
C LiuA Hjern

Abstract

To investigate the effects of maternal and paternal depression on the risk for preterm birth. National cohort study. Medical Birth Register of Sweden, 2007-2012. A total of 366 499 singleton births with linked information for parents' filled drug prescriptions and hospital care. Prenatal depression was defined as having filled a prescription for an antidepressant drug or having been in outpatient or inpatient hospital care with a diagnosis of depression from 12 months before conception until 24 weeks after conception. An indication of depression after 12 months with no depression was defined as 'new depression', whereas all other cases were defined as 'recurrent depression'. Odds ratios (ORs) for very preterm (22-31 weeks of gestation) and moderately preterm (32-36 weeks of gestation) births were estimated using multinomial logistic regression models. After adjustment for maternal depression and sociodemographic covariates, new paternal prenatal depression was associated with very preterm birth [adjusted OR (aOR) 1.38, 95% confidence interval (95% CI) 1.04-1.83], whereas recurrent paternal depression was not associated with an increased risk of preterm birth. Both new and recurrent maternal prenatal depression were associated w...Continue Reading

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Citations

Jun 23, 2016·American Journal of Obstetrics and Gynecology·Rebecca J BaerLaura L Jelliffe-Pawlowski
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Jun 21, 2017·Child Abuse & Neglect·Kenji TakeharaRintaro Mori
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