PMID: 2098597Dec 1, 1990Paper

Preoperative aspects of blood rheology in patients who developed multiple organ failure following cardiac surgery

Masui. The Japanese journal of anesthesiology
T Kato, N Tsushima

Abstract

The relationship between preoperative hemorheology and postoperative course was studied in 38 patients who had undergone open heart surgery for valvular diseases (mean age, 53 +/- 2 S.E. years). Twelve patients had multiple organ failures (MOF) one week after surgery, while the remaining 26 patients were in satisfactory condition. The hematocrit (Ht) was 34.8 +/- 1.6 S.E.% in patients with MOF and it was 40.4 +/- 0.9 S.E.% in patients without MOF. The difference was significant. Blood viscosities (eta) at shear rates of 94.5 sec-1 and 0.376 sec-1 also were significantly lower in patients with MOF compared with those without MOF. However, oxygen delivery (Ht/eta at a shear rate of 94.5 sec-1) in terms of hemorheology, plasma viscosity, and erythrocyte deformability were not significantly different between the two groups. These data suggest that patients with a low hematocrit and a low viscosity are likely to suffer from MOF following surgery.

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