Preoperative assessment of complete tumour resection by magnetic resonance imaging in patients undergoing pelvic exenteration

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Dirk Michael FornerBjoern Lampe

Abstract

To evaluate whether preoperative magnetic resonance imaging (MRI) allows prediction of complete tumour resection in patients planned for pelvic exenteration (PE). Data of all patients treated by PE at a gynaecologic cancer centre between 6/1999 and 5/2005 were studied retrospectively. Preoperative MRI scans were re-analysed blindly with respect to invasion of neighbouring organs, muscular pelvic side wall, vessels and lymph nodes by an experienced team of radiologist and gynaecologic oncologist, finally also giving estimation whether complete removal of tumour would be feasible. 43 patients were identified: all of them underwent PE. The histopathological investigation of the exenteration specimen demonstrated microscopic complete resection status in 20 cases (46.5%). None of the investigated parameter showed a correlation to complete resection of tumour. Sensitivity for final microscopic results relative to preoperative prediction by radiographic findings was 85%, specificity was 52%. The positive predictive value for tumour-free status was 60% (17/28), the negative 80% (12/15). Preoperative MRI cannot predict the surgical outcome with sufficient accuracy, hence on its own is inappropriate for prediction of complete tumour rese...Continue Reading

References

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Citations

Sep 14, 2010·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·U HegerJ Weitz
Feb 15, 2016·Journal de gynécologie, obstétrique et biologie de la reproduction·H SardainJ Levêque
Dec 24, 2011·Gynécologie, obstétrique & fertilité·G FerronD Querleu
Apr 30, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·H SardainJ Levêque
Jun 7, 2011·American Journal of Obstetrics and Gynecology·Dirk Michael Forner, Bjoern Lampe
Jan 21, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Vito ChianteraGiuseppe Filiberto Vercellino
Jan 31, 2021·Journal of Robotic Surgery·Vandana JainSudhir Rawal

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