Preoperative chronic opioid use and its impact on early complications in bariatric surgery: a Swedish nationwide cohort study of 56,183 patients.

Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery
Martin L Skogar, Magnus Sundbom

Abstract

The association between severe obesity and chronic pain makes opioid use common among bariatric patients. Preoperative opioid use has been identified as a risk factor in other surgical procedures. To examine the impact of preoperative opioid use on complications after primary bariatric surgery. Sweden. All primary laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) patients from 2007-2017 were identified in the Scandinavian Obesity Surgery Register. Prescriptions for opioids within 90 days prior to surgery were retrieved from the Swedish Prescribed Drug Register and converted into oral morphine equivalents (OMEs). Patients with ≥2 prescription of opioids within 90 days prior to surgery were defined as chronic opioid users. Generalized linear regression was used to adjust for age, sex, body mass index, procedure type, year of operation, and co-morbidities. Of the 56,183 patients who had undergone primary LRYGB (n = 49,615) or LSG (n = 6568), 17.5% (n = 9825) had at least 1 prescription of opioids prior to surgery, of which 4.3% (n = 2390) were defined as chronic opioid users. Chronic opioid use was associated with a higher risk of severe complications (Clavien Dindo grade ≥ 3b; odds ratio [OR]...Continue Reading

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Citations

Aug 11, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Bjarni VidarssonMagnus Sundbom

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