Preoperative colonization in pediatric cardiac surgery and its impact on postoperative infections

Paediatric Anaesthesia
Simona SilvettiElena Costa

Abstract

Patients with congenital heart defects are frequently hospitalized before surgery. This exposes them to a high risk for pathogen colonization. There are limited data on colonization prevalence in the pediatric cardiac population, and limited data concerning its potential role in the risk of developing infections after cardiac surgery. This study aimed to verify the impact of preoperative colonization on postoperative infections in a population of pediatric cardiac surgery patients coming from Italy and developing countries. This was a retrospective study conducted in all the patients aged ≤18 years who underwent pediatric open-heart surgery in the year 2015. Clinical data were retrieved from the institutional database for cardiac surgery patients. Data on swab cultures were retrieved from the laboratory database. Swab colonization was tested for association with infection and other outcomes. Among 169 children who performed the screening for pathogen colonization, 50% had at least one positive swab. Italian patients were (P=.001) less likely to be colonized with respect to foreign patients (relative risk 0.17, 95% CI 0.09-0.35). Postoperative infections in colonized patients occurred at a similar rate as in noncolonized patient...Continue Reading

References

Jan 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D A Goldmann, W C Huskins
Mar 30, 2005·Lancet·Anita K M ZaidiDonald A Goldmann
Aug 26, 2006·The Journal of Hospital Infection·A KonvalinkaI W Fong
Oct 9, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Deborah S YokoeDavid Classen
Mar 7, 2013·Surgical Infections·Dale W BratzlerUNKNOWN Society for Healthcare Epidemiology of America (SHEA)
Jun 8, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jongha ParkKamyar Kalantar-Zadeh
Nov 26, 2013·Critical Care Nursing Clinics of North America·Jacqueline B Broadway-Duren, Hillary Klaassen
Feb 3, 2015·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Tomoyuki Katayanagi
Jun 10, 2016·Archives of Medical Science : AMS·Radoslaw JaworskiJacek Zielinski

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