Preoperative Coronary Stenosis Is a Determinant of Early Vascular Outcome after Carotid Endarterectomy

Journal of Clinical Neurology
Jung Hwa KimDae Il Chang

Abstract

The benefit of carotid endarterectomy (CEA) is directly influenced by the risk of perioperative adverse outcomes. However, patient-level risks and predictors including coronary stenosis are rarely evaluated, especially in Asian patients. The aim of this study was to determine the relationship between the vascular risk factors underlying CEA, including coronary stenosis, and postoperative outcome. One hundred and fifty-three consecutive CEAs from our hospital records were included in this analysis. All patients underwent coronary computed tomography angiography before CEA. Data were analyzed to determine the vascular outcomes in patients with mild-to-moderate vs. severe coronary stenosis and high vs. standard operative risk, based on the criteria for high operative risk defined in the Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy (SAPPHIRE) trial. The vascular outcome was defined as the occurrence of postoperative (≤30 days) stroke, myocardial infarction (MI), or death. An adverse vascular outcome occurred in 8 of the 153 CEAs, with 6 strokes, 2 MIs, and 3 deaths. The vascular outcome differed significantly between the groups with mild-to-moderate and severe coronary stenosis (p=0.024), but...Continue Reading

References

Mar 1, 1992·Stroke; a Journal of Cerebral Circulation·M I Chimowitz, G B Mancini
Apr 1, 1994·Journal of Vascular Surgery·D J MusserJ F Reed
Dec 9, 1998·Journal of Vascular Surgery·D S KuceyJ V Tu
Sep 2, 1999·Stroke; a Journal of Cerebral Circulation·G G FergusonH J Barnett
Jan 7, 2003·Journal of Vascular Surgery·Antonios P GasparisJohn J Ricotta
May 12, 2004·Lancet·A HallidayUNKNOWN MRC Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group
Oct 8, 2004·The New England Journal of Medicine·Jay S YadavUNKNOWN Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy Investigators
Nov 29, 2008·The New England Journal of Medicine·Julie M MillerJoão A C Lima
Dec 20, 2008·Journal of the American College of Cardiology·W Bob MeijboomPim J de Feyter
Dec 17, 2009·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·G IlluminatiL Tritapepe
May 28, 2010·The New England Journal of Medicine·Thomas G BrottUNKNOWN CREST Investigators
Dec 15, 2010·Journal of the American College of Cardiology·Edward A HultenTodd C Villines
Oct 13, 2011·Nature Reviews. Cardiology·A Ross Naylor
Apr 5, 2012·Circulation. Cardiovascular Quality and Outcomes·Keun-Hwa JungUNKNOWN Korean Stroke Registry Study Group

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Citations

Jun 13, 2017·Frontiers in Neurology·Sung Hyuk Heo, Cheryl D Bushnell
Jun 30, 2019·Scandinavian Cardiovascular Journal : SCJ·Joana Alves-FerreiraSandrina F Braga
Jul 19, 2019·Khirurgiia·A N KazantsevE O Soldatov
Jul 3, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Xin LiuWanqing Wu

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