Preoperative embolization of Castleman's disease using microspheres

The Annals of Thoracic Surgery
Warren SweeKlaus D Hagspiel

Abstract

Castleman's disease is a rare form of lymph node hyperplasia most commonly presenting as a solitary hypervascular mediastinal mass. Surgical resection is the treatment of choice, but this can be associated with significant blood loss due to its hypervascularity. We report two cases with a preoperative diagnosis of mediastinal Castleman's disease in whom preoperative embolization with Trisacryl gelatin microspheres (Biosphere Medical, Rockland, MA) was performed. Compared with the literature, a decrease in the amount of perioperative bleeding was noted in both cases.

References

Dec 16, 1998·Annals of Internal Medicine·J HerradaW Pugh
Nov 10, 2001·Hematology·Timothy GreinerThomas G. Gross
Jan 16, 2003·Chest·Peter A SeirafiFred H Edwards
Jul 5, 2003·The Annals of Thoracic Surgery·Sheung-Fat KoWei-Jen Chen
Jul 1, 1956·Cancer·B CASTLEMANV P MENENDEZ

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Citations

Nov 4, 2011·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Nebojsa MarićOlga Tasić Radić
Feb 6, 2014·World Journal of Surgical Oncology·Austin D WilliamsWilbur B Bowne
Jul 10, 2021·European Journal of Haematology·Meera MohanFrits van Rhee

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Castleman Disease

Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.