Preoperative evaluation of oesophageal adenocarcinoma

Best Practice & Research. Clinical Gastroenterology
Lauren G Khanna, Frank G Gress

Abstract

The preoperative evaluation of oesophageal adenocarcinoma involves endoscopic ultrasound (EUS), computed tomography (CT), and positron emission tomography (PET). With routine Barrett's oesophagus surveillance, superficial cancers are often identified. EUS, CT and PET have a limited role in the staging of superficial tumours. Standard EUS has limited accuracy, but high frequency ultrasound miniprobes are valuable for assessing tumour stage in superficial tumours. However, the best method for determining depth of invasion, and thereby stage of disease, is endoscopic mucosal resection. In contrast, in advanced oesophageal cancers, a multi-modality approach is crucial. Accurate tumour staging is very important since the treatment of advanced cancers involves a combination of chemotherapy, radiation, and surgery. EUS is very useful for staging of the tumour and nodes. High frequency ultrasound miniprobes provide the ability to perform staging when the lesion is obstructing the oesophageal lumen. CT and PET provide valuable information regarding node and metastasis staging.

References

May 1, 1992·Endoscopy·J C SouquetR Lambert
Jul 1, 1994·Gastrointestinal Endoscopy·M F CatalanoJ Van Dam
Aug 15, 1996·The New England Journal of Medicine·T N WalshT P Hennessy
Feb 1, 1997·AJR. American Journal of Roentgenology·F L FlanaganJ D Cooper
Oct 6, 1997·The Annals of Thoracic Surgery·M I BlockJ D Cooper
Apr 4, 1998·The Annals of Thoracic Surgery·T W RiceJ R Goldblum
Mar 18, 1999·The New England Journal of Medicine·J LagergrenO Nyrén
Apr 10, 1999·The Annals of Thoracic Surgery·C E ReedR H Hawes
Jun 22, 1999·Annals of Internal Medicine·J LagergrenO Nyrén
Apr 19, 2002·JAMA : the Journal of the American Medical Association·Nicholas Shaheen, David F Ransohoff
Jun 7, 2002·Lancet·UNKNOWN Medical Research Council Oesophageal Cancer Working Group
Nov 24, 2004·Gastrointestinal Endoscopy Clinics of North America·Kenjiro YasudaMasatsugu Nakajima
Nov 24, 2004·Gastrointestinal Endoscopy Clinics of North America·Ian D Penman, Elaine Henry
Apr 20, 2005·Virchows Archiv : an International Journal of Pathology·Marinke WesterterpJan J B van Lanschot
Apr 7, 2010·Annals of Surgical Oncology·Thomas W RiceValerie W Rusch
Sep 14, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Patrick E YoungMark Riddle
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
Aug 25, 2012·Gut·Gustaf EdgrenOlof Nyrén
Jan 11, 2013·Cancer·Chin HurEric J Feuer

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Citations

Jan 13, 2016·Expert Review of Gastroenterology & Hepatology·George Triadafilopoulos, Junichi Akiyama
May 8, 2018·Journal of Magnetic Resonance Imaging : JMRI·Shaocheng ZhuBin Song
Aug 14, 2015·World Journal of Gastroenterology : WJG·Grigory G KarmazanovskyDmitry V Kalinin
Aug 13, 2021·Endoscopic Ultrasound·Hans SeifertChristoph F Dietrich

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