Preoperative MR Imaging to Differentiate Chordoid Meningiomas from Other Meningioma Histologic Subtypes

AJNR. American Journal of Neuroradiology
J D BaalJ E Villanueva-Meyer

Abstract

Chordoid meningiomas are uncommon WHO grade II primary intracranial neoplasms that possess unique chordoid histology and follow an aggressive clinical course. Our aim was to assess the utility of qualitative MR imaging features and quantitative apparent diffusion coefficient values as distinguishing preoperative MR imaging metrics to identify and differentiate chordoid histology from other meningioma histologic subtypes. Twenty-one patients with meningiomas with chordoid histology, which included both chordoid meningiomas (>50% chordoid histology) and meningiomas with focal chordoid histology (<50% chordoid histology) with available preoperative MR imaging examinations, including diffusion-weighted imaging, were identified. Qualitative imaging features and quantitative ADC values were compared between meningiomas with chordoid histology and 42 nonchordoid meningiomas (29 WHO grade I, eleven WHO grade II, and 2 WHO grade III). The median ADC (10-3mm2/s) of meningiomas with chordoid histology was significantly higher than nonchordoid meningiomas (1.16 versus 0.92, P < .001), as was the median normalized ADC (1.60 versus 1.19, P < .001). In subgroup analysis, the median and normalized ADC values of chordoid meningiomas (n = 11) we...Continue Reading

References

Mar 6, 1999·Journal of Neurosurgery·S NakasuJ Handa
Jul 15, 2000·The American Journal of Surgical Pathology·M E CouceB W Scheithauer
Apr 2, 2008·Neuroradiology·Hao ZhangMatthijs Oudkerk
Nov 6, 2012·AJNR. American Journal of Neuroradiology·K W YeomN J Fischbein
Jan 9, 2014·Insights Into Imaging·J WattsT Sutherland
Jul 1, 2016·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Stefan SchobEckhard Fiedler
Aug 29, 2016·Translational Oncology·Stefan SchobAlexey Surov
Nov 18, 2017·PloS One·Thibaud P CorollerHugo J W L Aerts
Feb 3, 2018·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Georg Alexander GihrStefan Schob

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