PMID: 3767008Nov 1, 1986Paper

Preoperative oral fluids: is a five-hour fast justified prior to elective surgery?

Anesthesia and Analgesia
J R MaltbyE A Shaffer

Abstract

The effects of preoperative oral administration of 150 ml fluid were studied prospectively in 140 unpremedicated, ambulatory outpatients presenting for first trimester therapeutic abortion. Intraoperative gastric fluid volume, pH, and rate of gastric emptying were measured in the four groups to which patients were randomly assigned. At an average time of 2 1/2 hr preoperatively all patients received either oral ranitidine, 150 mg, or a placebo tablet, with the nonabsorbable marker dye bromosulphthalein (BSP, 50 mg in 10 ml water, followed by either 150 ml water or no further fluid. The effect of volume ingested was assessed by comparing the volume of gastric contents obtained by gastric tube suctioning at the completion of surgery in the two groups given placebos. The gastric volume was significantly less in patients given 150 ml water (17.6 +/- 14.5) than in those given only BSP (26.7 +/- 18.9) (P less than 0.02), and was further significantly decreased in the two groups given ranitidine (8.3 +/- 7.3, 9.5 +/- 7.7 ml) (P less than 0.001). Mean pH values were significantly higher in the two ranitidine groups (5.52 +/- 1.79, 5.03 +/- 1.79) than in the two placebo groups (1.75 +/- 0.94, 1.92 +/- 1.27). The combination of a residua...Continue Reading

Citations

May 1, 1993·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J R Maltby
Nov 1, 1995·Journal of Clinical Anesthesia·M S Schreiner, S C Nicolson
Jul 1, 1991·Acta Anaesthesiologica Scandinavica·J S JahrD R Cook
Nov 1, 1994·Acta Anaesthesiologica Scandinavica·E SøreideP A Steen
Aug 1, 1995·Acta Anaesthesiologica Scandinavica·E SøreideP A Steen

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