Preparation and characterization of anodized titanium surfaces and their effect on osteoblast responses

The Journal of Oral Implantology
Kyo-Han KimJoo L Ong

Abstract

In this study, titanium (Ti) surface was modified by anodizing with a mixture of beta-glycerophosphate sodium and calcium (Ca) acetate, and the anodized surfaces were characterized by scanning electron microscopy, X-ray diffraction, and electron probe microanalysis. In vitro osteoblast response to anodized oxide was also evaluated. The anodic oxide produced was observed to have interconnected pores (0.5-2 microm in diameter) and intermediate roughness (0.60-1.00 microm). In addition, anodic oxide was observed to have amorphous and anatase oxide. Calcium and phosphorus ions were deposited on the Ti oxide during anodization. Osteoblast differentiation, as indicated by alkaline phosphatase production, was enhanced on anodized surfaces. It was thus concluded from this study that Ca phosphate can be deposited on Ti surfaces by anodization. It was also concluded that the phenotypic expression of osteoblast was enhanced by the presence of Ca phosphate and higher roughness on anodized Ti surfaces.

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Citations

Feb 16, 2008·Journal of Biomedicine & Biotechnology·M JägerR Krauspe
Mar 14, 2009·Dental Materials Journal·Kyo-Han Kim, Narayanan Ramaswamy
Aug 25, 2007·Nanomedicine·Ganesan Balasundaram, Thomas J Webster
Jul 30, 2009·Expert Opinion on Drug Delivery·Lei Yang, Thomas J Webster
Jul 10, 2007·Journal of Biomedical Materials Research. Part a·Ganesan BalasundaramThomas J Webster
Mar 1, 2017·Regenerative Biomaterials·Yan ZhangBo Feng

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