Preparation and Characterization of Azadirachtin Alginate-Biosorbent Based Formulations: Water Release Kinetics and Photodegradation Study

Journal of Agricultural and Food Chemistry
Francisco Flores-CéspedesManuel Fernández-Pérez

Abstract

The botanical insecticide azadirachtin was incorporated in alginate-based granules to obtain controlled release formulations (CRFs). The basic formulation [sodium alginate (1.47%) - azadirachtin (0.28%) - water] was modified by the addition of biosorbents, obtaining homogeneous hybrid hydrogels with high azadirachtin entrapment efficiency. The effect on azadirachtin release rate caused by the incorporation of biosorbents such as lignin, humic acid, and olive pomace in alginate formulation was studied by immersion of the granules in water under static conditions. The addition of the biosorbents to the basic alginate formulation reduces the rate of release because the lignin-based formulation produces a slower release. Photodegradation experiments showed the potential of the prepared formulations in protecting azadirachtin against simulated sunlight, thus improving its stability. The results showed that formulation prepared with lignin provided extended protection. Therefore, this study provides a new procedure to encapsulate the botanical insecticide azadirachtin, improving its delivery and photostability.

References

Jan 21, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·A R KulkarniM H Mehta
Jun 10, 2004·Journal of Agricultural and Food Chemistry·Manuel Fernández-PérezFrancisco Javier Garrido-Herrera
Aug 18, 2005·Journal of Agricultural and Food Chemistry·M Fernández-PérezS Pérez-García
Jun 26, 2007·Chemosphere·F Flores CéspedesM Fernández Pérez
Nov 26, 2009·Carbohydrate Research·Hisao TomidaMakoto Anraku
Mar 12, 2010·Journal of Agricultural and Food Chemistry·Mohanji SaxenaAnirudh Sharma
Dec 3, 2014·Biotechnology Advances·Jhones Luiz de OliveiraLeonardo Fernandes Fraceto
Apr 11, 2015·Carbohydrate Polymers·Maria Cristina StracciaPaola Laurienzo

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Citations

Apr 19, 2017·Journal of Agricultural and Food Chemistry·Benkai QinGuang Han
Jun 10, 2017·Pharmaceutical Development and Technology·Ana Henriques MotaCatarina Pinto Reis
Jun 21, 2019·Environmental Science and Pollution Research International·Arumugam Dhanesh GandhiAdikesavan Selvi
Dec 16, 2018·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sandeep KumarKi-Hyun Kim
Mar 17, 2020·International Journal of Biological Macromolecules·Francisco Flores-CéspedesManuel Fernández-Pérez

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