Preparation and characterization of guar gum nanoparticles

International Journal of Biological Macromolecules
R S SoumyaEmilia T Abraham

Abstract

The preparation of guar gum nanoparticles by nanoprecipitation and cross-linking method is reported here. Nanoparticles act as potential carries for several classes of drugs and cosmetics. It has been found that the formation of nanoparticles depends upon the molecular mass of the galactomannan, solvent, surfactant, cross-linker and agitation. The galactomannan nanoparticles functionalized with lipase and crystal violet as model drugs were used for release study. The sizes of the particles in suspension have been measured by light scattering technique. The size and the morphology of the particles have been determined by electron microscopy studies. Optimized method produced spherical nanoparticles of size approximately 20-50 nm with a polydispersity index in the range 0.1-0.4.

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Nov 18, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Geneviève GaucherJean-Christophe Leroux
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Citations

Jun 10, 2014·Dose-response : a Publication of International Hormesis Society·Iris R BellWayne B Jonas
Aug 16, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Soumini MondalKanchan Maji
Mar 25, 2018·International Journal of Biological Macromolecules·Gaurav SharmaFlorian J Stadler
Aug 21, 2019·Carbohydrate Polymers·Zahra Moradi, Nastaran Kalanpour

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