Preparation and characterization of N-benzoyl-O-acetyl-chitosan

International Journal of Biological Macromolecules
Jinping CaiJingjing Li

Abstract

A novel amphipathic chitosan derivative, N-benzoyl-O-acetyl-chitosan (BACS), was prepared by using the selective partial acylation of chitosan (CS), benzoyl chloride, and acetic acid under high-intensity ultrasound. The chemical structure and physical properties of BACS were characterized by FTIR, (1)H NMR, TGA, and XRD techniques. The degrees of substitution of benzoyl and acetyl for the chitosan derivatives were 0.26 and 1.15, respectively, which were calculated from the peak areas in NMR spectra by using the combined integral methods. The foaming properties of CS and BACS were determined and the results suggested BACS had better foam capacity and stability than those of chitosan. In addition, the antimicrobial activities of CS and BACS were also investigated against two species of bacteria (Escherichia coli and Staphylococcus aureus) and a fungus (Aspergillus niger), the results indicated that the antibacterial and antifungal activities of BACS were much stronger than those of the parent chitosan. These findings suggested that BACS was preferable for use as a food additive with a dual role of both foaming agent and food preservative.

References

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Citations

Jan 29, 2016·International Journal of Biological Macromolecules·Zihao Wei, Yanxiang Gao
Nov 5, 2016·International Journal of Biological Macromolecules·Fengling TangGuangqian Lan
Apr 1, 2017·Applied Microbiology and Biotechnology·Faez Iqbal KhanMd Imtaiyaz Hassan
Apr 5, 2017·International Journal of Biological Macromolecules·Wenqiang TanZhanyong Guo
Jan 17, 2020·International Journal of Molecular Sciences·Wenqian WangKai Zhao
Jan 2, 2021·Polymers·Agnieszka PiegatAgata Goszczyńska
Jul 30, 2021·International Journal of Biological Macromolecules·Chandrima ModakAwanish Kumar
Aug 11, 2021·Polymers·Kamla PathakTapan Behl

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