Preparation and in vitro evaluation of polycaprolactone/PEG/bioactive glass nanopowders nanocomposite membranes for GTR/GBR applications

Materials Science & Engineering. C, Materials for Biological Applications
Shiva Soltani DehnaviShahin Bonakdar

Abstract

In the present study, nanocomposite membranes are investigated using poly-ε-caprolactone (PCL), polyethylene glycol (PEG) and bioactive glass nanopowders (BGs) synthesized via solvent casting method with different reinforcement rates of BGs consisting of 3, 5 and 7 wt% for regenerating the periodontal tissue in vitro. These prepared membranes were evaluated by a vast range of essential tests; including Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Transmition-electron microscopy (TEM), tensile testing before and after soaking in PBS solution, degradation and contact angle assessments as well as cell culture assays. In spite of the fact that the percentage of Cu incorporated into BGs was trivial, this negligible amount exerted major cytotoxic impact upon cells during in vitro cell tests. According to the results, the blended-membrane contained 7 wt% copper-free BGs indicated optimum characteristics including satisfactory mechanical and biodegradation features, more wettable surface, higher proliferation rates of adipose-derived stem cells (ADSCs), superior ALP activity and brilliant bone mineralization capacity which was confirmed by Alizarin red assay. As a consequence, it can be used as a ...Continue Reading

References

Jun 1, 1986·Metabolism: Clinical and Experimental·J R Farley, D J Baylink
Apr 6, 2001·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·T BaroniG Abbritti
Oct 17, 2003·European Cells & Materials·P A Gunatillake, R Adhikari
Nov 19, 2003·Journal of Biomedical Materials Research. Part a·Anil ThapaKaren M Haberstroh
May 26, 2004·International Journal of Pharmaceutics·V R SinhaA Trehan
Sep 29, 2005·Injury·Peter V GiannoudisEleftherios Tsiridis
Nov 22, 2005·Lancet·Bruce L PihlstromNewell W Johnson
Mar 30, 2007·Acta Biomaterialia·Georgia Chouzouri, Marino Xanthos
Jul 27, 2007·Journal of Dental Research·T WaltimoM Zehnder
Oct 18, 2008·Progress in Neurobiology·Won Hyuk SuhYoo-Hun Suh
Feb 4, 2010·Journal of Biomedical Materials Research. Part a·V MortazaviB Nasr Esfahani
Jun 24, 2010·Biomedical Materials·Leila MontazeriSayfoddin Javadian
Oct 4, 2011·Journal of Controlled Release : Official Journal of the Controlled Release Society·Tapan K Dash, V Badireenath Konkimalla
Dec 1, 2011·Journal of Materials Science. Materials in Medicine·M Mehdikhani-NahrkhalajiS M Razavi
Jan 19, 2012·International Journal of Biomaterials·Aous A AbdulmajeedTimo O Närhi
Feb 11, 2012·Journal of Biomedical Materials Research. Part a·M FarokhiM A Shokrgozar
May 18, 2012·Dental Materials : Official Publication of the Academy of Dental Materials·Marco C BottinoGregg M Janowski
Jan 12, 2013·Biological Trace Element Research·Eun-Jin KimMi-Kyeong Choi
Dec 4, 2013·International Journal of Biological Macromolecules·A P HurtN J Coleman
Dec 11, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Lijun JiXiaoli Song
Feb 14, 2015·Acta Biomaterialia·Charlène B S S DanouxPamela Habibovic
Dec 4, 2016·Colloids and Surfaces. B, Biointerfaces·Kai ZhengAldo R Boccaccini
Mar 24, 2017·Journal of Animal Science and Biotechnology·Lefei JiaoCaihong Hu

❮ Previous
Next ❯

Citations

Nov 6, 2018·Current Stem Cell Research & Therapy·Dilcele Silva Moreira DziedzicKatherine Athayde Teixeira de Carvalho
Feb 27, 2020·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Songou ZhangWenqing Liang
Mar 1, 2019·Journal of Functional Biomaterials·Alejandra Ruiz-ClavijoNichola J Coleman
Aug 28, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zoi TerzopoulouDimitrios Bikiaris
Oct 23, 2020·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Qinfeng DingKaili Lin
Jun 22, 2019·Colloids and Surfaces. B, Biointerfaces·Marie DubusHalima Kerdjoudj
Jun 7, 2021·Colloids and Surfaces. B, Biointerfaces·Peiyi LiXinchun Zhang
Jun 16, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kai ChenYubo Fan
Oct 9, 2019·International Journal of Biological Macromolecules·Danilo M Dos SantosDaniel S Correa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Shaozhi FuZhiyong Qian
Materials Science & Engineering. C, Materials for Biological Applications
Sedef Tamburaci, Funda Tihminlioglu
Materials Science & Engineering. C, Materials for Biological Applications
Maryam Masoudi RadSeeram Ramakrishna
Journal of Materials Science. Materials in Medicine
Sedef Tamburaci, Funda Tihminlioglu
© 2022 Meta ULC. All rights reserved