Preparation and physicochemical properties of the complex of naringenin with hydroxypropyl-beta-cyclodextrin.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Jiping WenYongyi Zhu

Abstract

In this study a complex of naringenin with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) was prepared to improve the hydrophilicity of naringenin. The physicochemical properties of the complex were analyzed by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), X-ray diffractometry (XRD), differential scanning calorimetry (DSC). The result showed that naringenin had been molecularly dispersed in the HP-beta-CD matrix, not forming a new compound and HPLC analysis showed that the solubility of naringenin in water was enhanced from 4.38 microg/mL to 1,272.31 microg/mL.

References

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Citations

Sep 10, 2013·Applied Biochemistry and Biotechnology·Nguyen Huy ThuanJae Kyung Sohng
Dec 13, 2012·Pathology Oncology Research : POR·Nechikkad SulfikkaraliRamadas Madhavan Nirmal
Apr 20, 2013·Food & Function·Yishai AviorYaakov Nahmias
Apr 22, 2015·Seminars in Cancer Biology·Mark A FeitelsonSomaira Nowsheen
Jul 23, 2014·Drug Delivery·Neha Sharma, Ashish Baldi
Dec 17, 2014·Nutrition and Cancer·Irfan Ahmad Mir, Ashu Bhan Tiku
Sep 12, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Paulina StrugałaJanina Gabrielska
Jul 4, 2018·Drug Development and Industrial Pharmacy·Sumathi RajamaniSivakumar Thangavelu
Apr 4, 2017·Oxidative Medicine and Cellular Longevity·Maria Rosaria LauroGiovanni Puglisi
Apr 16, 2020·Nanomaterials·Marta G FusterGloria Víllora
Nov 4, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·María Isabel Rodríguez-LópezEstrella Núñez-Delicado
Aug 19, 2021·Molecular and Cellular Biochemistry·Artem G VeikoIlya B Zavodnik
Apr 9, 2019·Journal of Agricultural and Food Chemistry·Xiaomei LyuWei Ning Chen

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Methods Mentioned

BETA
X-ray

Software Mentioned

Universal Analysis 2000
Empower

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