Preparation and Thickness Profile of Endothelial Keratoplasty Lenticules from Donated Whole Eyes with Previous Photorefractive Keratectomy

Journal of Ophthalmic & Vision Research
Mozhgan Rezaei KanaviMohammad Ali Javadi

Abstract

To describe the preparation and thickness profiles of endothelial keratoplasty lenticules harvested from eyes with previous photorefractive keratectomy (PRK). Donor whole eyes that underwent PRK were subjected to microkeratome-assisted dissection for Descemet stripping automated endothelial keratoplasty. Specular microscopy and Visante optical coherence tomography were performed on precut corneas. Endothelial cell indices and thickness profiles of endothelial keratoplasty lenticules were statistically analyzed. Postoperative reports for transplanted lenticules were recorded. Over a 6-month period, 2,929 whole eyes from 1,471 donors were screened for PRK. Twenty-five (0.85%) eyes from 14 donors were diagnosed with disciform haziness due to prior PRK and were used uneventfully for preparation of endothelial keratoplasty lenticules. Mean endothelial cell count was 3164.6 ± 311.0/mm2 and mean central posterior lenticule thickness was 128 ± 34 μm. Posterior lenticules revealed an increase in thickness from the central to peripheral cornea (mean increase of 26.2 μm at pericentral and 90.4 μm at peripheral locations). Mean increase in thickness was statistically different between two peripheral locations (74.5 μm vs. 108.1 μm, P = 0.0...Continue Reading

References

May 19, 2007·American Journal of Ophthalmology·Vasilios F DiakonisMarinos M Markomanolakis
May 24, 2008·Journal of Cataract and Refractive Surgery·Nader NassiriNariman Nassiri
Sep 25, 2008·Journal of Cataract and Refractive Surgery·Li-Quan ZhaoHuang Zhu
May 17, 2011·BMC Ophthalmology·Irene C Kuo
Jul 15, 2016·Journal of Ophthalmic & Vision Research·Mozhgan Rezaei KanaviSare Safi

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Citations

Nov 2, 2017·Journal of Ophthalmic & Vision Research·Neslihan Dilruba KoseogluPedram Hamrah

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Methods Mentioned

BETA
dissection

Software Mentioned

SPSS

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