Preparation and time-gated luminescence bioimaging applications of long wavelength-excited silica-encapsulated europium nanoparticles

Nanoscale
Lu TianJingli Yuan

Abstract

Silica-encapsulated luminescent lanthanide nanoparticles have shown great potential as biolabels for various time-gated luminescence bio-detections in recent years. The main problem of these nano-biolabels is their short excitation wavelengths within the UV region. In this work, a new type of silica-encapsulated luminescent europium nanoparticle, with a wide excitation range from UV to visible light in aqueous solutions, has been prepared using a conjugate of (3-isocyanatopropyl)triethoxysilane bound to a visible light-excited Eu(3+) complex, 2,6-bis(1',1',1',2',2',3',3'-heptafluoro-4',6'-hexanedion-6'-yl)-dibenzothiophene-Eu(3+)-2-(N,N-diethylanilin-4-yl)-4,6-bis(pyrazol-1-yl)-1,3,5-triazine (IPTES-BHHD-Eu(3+)-BPT conjugate), as a functionalized precursor. The nanoparticles, which are prepared by the copolymerization of the IPTES-BHHD-Eu(3+)-BPT conjugate, tetraethyl orthosilicate and (3-aminopropyl)triethoxysilane in a water-in-oil reverse microemulsion consisting of Triton X-100, n-octanol, cyclohexane and water in the presence of aqueous ammonia, are monodisperse, spherical and uniform in size. Their diameter is 42 ± 3 nm and they are strongly luminescent with a wide excitation range from UV to ∼475 nm and a long luminescen...Continue Reading

References

Sep 18, 2003·Journal of the American Chemical Society·Xiaojun ZhaoWeihong Tan
Oct 13, 2004·Proceedings of the National Academy of Sciences of the United States of America·Xiaojun ZhaoWeihong Tan
Oct 13, 2006·Journal of the American Chemical Society·Bo SongJingli Yuan
Mar 8, 2007·Bioconjugate Chemistry·Lin WangWeihong Tan
Oct 3, 2007·Journal of Fluorescence·Pascal KadjaneRaymond Ziessel
Jun 7, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Xiaofan WenXicheng Ai
Feb 16, 2010·Chemical Reviews·Jean-Claude G Bünzli
Mar 20, 2010·Physical Chemistry Chemical Physics : PCCP·Fumin XueYuan Wang
Apr 22, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Wei DengEwa M Goldys
Jul 24, 2010·Analytical and Bioanalytical Chemistry·Guannan WangXingguang Su

❮ Previous
Next ❯

Citations

Feb 19, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·M VenkateswaruluRik Rani Koner
Oct 1, 2013·Dalton Transactions : an International Journal of Inorganic Chemistry·M L P ReddyRani Pavithran
Oct 28, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Maria C GomesTito Trindade
May 5, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Lingjuan KongHaibin Chu
May 21, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·S TargonskaR J Wiglusz
Jun 18, 2014·Journal of the American Chemical Society·Xiaoqing XiongXiaojun Peng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.