Abstract
Chitosan is a commercially available derivative of chitin that has been extensively studied for its antimicrobial properties. In order to improve the water solubility and its biological activity, the chemical modification or derivatisation is attempted. In the present investigation, the chitosan prepared from the cuttlebone of Sepia kobiensis was being chemically modified by reacting it with orthophosphoric acid so as to obtain phosphorylated chitosan. Then the chitosan and phosphorylated chitosan were structurally characterized through FT-IR spectroscopy. Further the antibacterial activity of chitosan and phosphorylated chitosan was tested against clinically isolated human pathogens (Gram-positive: Streptococcus sp., Streptococcus pneumoniae and Staphylococcus aureus and Gram-negative: Escherichia coli, Vibrio cholerae, V. alginolyticus, Vibrio parahaemolyticus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella sp. and Proteus vulgaris) by well diffusion method and the Minimum Inhibitory Concentration (MIC) was also calculated. The results of the present study suggests that the chitosan and phosphorylated chitosan has concentration dependent antibacterial activity with variation against several pathogenic human pathoge...Continue Reading
Citations
Dec 25, 2019·Antimicrobial Agents and Chemotherapy·Alaa RiezkSimon L Croft
Apr 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Pasquale SaccoIvan Donati
May 30, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Claudio LuparelloMirella Vazzana
Mar 28, 2017·Veterinary World·Tarun Kumar VarunNarender Kumar
Mar 23, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lijie WeiZhanyong Guo
Feb 7, 2019·Pakistan Journal of Biological Sciences : PJBS·Dina SugiyantiSri Anggrahini
May 30, 2019·Journal of Medical Entomology·Hamidreza BasseriLaila Hosainpour
Jan 23, 2020·Marine Drugs·Mitchell JonesAlexander Bismarck
Apr 13, 2017·Environmental Science and Pollution Research International·Shima L HolderSrinivasa R Popuri
Jan 15, 2019·Applied Microbiology and Biotechnology·Shahia KhattakCheng Zhong
Nov 23, 2020·AAPS PharmSciTech·Noha NafeeOsama Y Abdallah
Nov 25, 2020·Marine Drugs·Kate SummerKirsten Benkendorff
Oct 23, 2020·Journal of Nanobiotechnology·Jolanta Pulit-ProciakMarcin Banach
Dec 20, 2017·Carbohydrate Polymers·Junlong WangJi Zhang
Sep 30, 2020·International Journal of Biological Macromolecules·Eman M KamelH M Abd El-Salam
Jul 12, 2020·International Journal of Biological Macromolecules·Kajal ChakrabortyMinju Joy
Apr 4, 2021·Journal of Biomedical Materials Research. Part a·Hamid Ait SaidAllal Barroug
Nov 19, 2018·International Journal of Biological Macromolecules·Amira M El-ShafeiMona T Al-Shemy
Aug 16, 2016·Carbohydrate Polymers·Imran KhanDeog-Hwan Oh
Jun 3, 2021·Foods·Joana GomesPaula Teixeira
Jun 11, 2021·Carbohydrate Research·Ajahar Khan, Khalid A Alamry
Apr 15, 2021·Nanotechnology·Marian RofealXianghui Qi
Aug 17, 2021·The Science of the Total Environment·Kevin MastersonNeil J Rowan
Aug 19, 2021·Applied Biochemistry and Biotechnology·Md Masirul AfrozNafisa Islam
Aug 24, 2021·Carbohydrate Polymers·E RincónA Jiménez-Quero