PMID: 8601927Apr 10, 1996Paper

Prepregnant weight in relation to risk of neural tube defects

JAMA : the Journal of the American Medical Association
M M WerlerA A Mitchell

Abstract

To examine the relation between prepregnant weight and the risk of neural tube defects (NTDs). Data were collected from 1988 to 1994 in a case-control surveillance program of birth defects. Study subjects were ascertained at tertiary care centers and birth hospitals in the greater metropolitan areas of Boston, Mass, and Philadelphia, Pa, and in southeastern Ontario. Cases were 604 fetuses or infants with an NTD identified within 6 months of delivery. Controls were 1658 fetuses or infants with other major malformations identified within 6 months of delivery. For 1992 to 1994, there were 93 control infants without major malformations. Relative risk of NTDs in infants or fetuses for different maternal weights. Relative to women who weighed 50 to 59 kg, risk of NTDs increased from 1.9 (95% confidence interval [CI], 1.2 to 2.9) for women weighing 80 to 89 kg to 4.0 (95% CI, 1.6 to 9.9) for women weighing 110 kg or more. When women were classified according to daily intake above or below the recommended level of 400 micrograms of folate, approximate threefold increases in risk were estimated for the heaviest weights in both groups. Intakes of 400 micrograms of folate or more reduced risk of NTDs by 40% among women weighing less than ...Continue Reading

Citations

Apr 23, 2008·European Journal of Endocrinology·Sarah J LewisGeorge Davey Smith
Dec 17, 2008·Women's Health·Murizah M Zain, Robert J Norman
Jan 23, 2010·Obstetrics and Gynecology·Joseph R BiggioDwight J Rouse
May 30, 2001·Primary Care Update for Ob/Gyns·M E. CogswellW H. Dietz
Aug 18, 2004·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Joel G RayPhilip R Wyatt
Jun 17, 2008·Epidemiology·Gary M Shaw, Suzan L Carmichael
Jan 1, 2010·American Journal of Epidemiology·Mahsa M YazdyMartha M Werler
Jul 6, 2004·American Journal of Epidemiology·Gary M ShawDonna M Schaffer
Sep 7, 2013·Critical Reviews in Food Science and Nutrition·Anja OsterhuesKarin B Michels
Jun 21, 2001·Epidemiology·Margaret L. Watkins And, Lorenzo D. Botto
Dec 23, 2004·Epidemiology·James L AndersonMartha M Werler
Feb 24, 2009·Epidemiology·Suzan L CarmichaelGary M Shaw
May 27, 2005·Drugs·Mátyás TrixlerTamás Tényi
Jul 9, 2004·Toxicology and Applied Pharmacology·Richard H FinnellThomas H Rosenquist
May 17, 2003·Birth Defects Research. Part A, Clinical and Molecular Teratology·D Kim WallerAllen A Mitchell
Dec 26, 2001·Teratology·D K WallerA E Scheuerle
Dec 18, 2002·Teratology·Gideon Koren
May 26, 2005·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Linda A BradleyUNKNOWN ACMG Laboratory Quality Assurance Committee
Sep 24, 2004·Obstetrical & Gynecological Survey·Elizabeth A McCarthyMichael Permezel
Mar 30, 2005·Obstetrical & Gynecological Survey·Lanniece F Hall, A George Neubert
Apr 8, 2009·Therapeutic Drug Monitoring·Carolyn TamGideon Koren
May 17, 2011·Therapeutic Drug Monitoring·Seth J SternGideon Koren
Jan 25, 2002·American Journal of Medical Genetics·Gary M ShawCynthia A Moore
Dec 15, 2004·Clinical Obstetrics and Gynecology·Francis S Nuthalapaty, Dwight J Rouse
Jul 26, 2005·Critical Care Nursing Quarterly·Rita Harrison Raymond
Dec 10, 2009·Current Opinion in Obstetrics & Gynecology·Joseph R Wax
Nov 5, 2013·Clinics in Perinatology·Jonathan R Swanson, Robert A Sinkin
Jun 28, 2007·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Amy P CaseRebecca Wood
Oct 6, 1997·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·M B Tinkle, B S Sterling
Feb 15, 2011·Gynécologie, obstétrique & fertilité·P Deruelle
Sep 18, 2010·Early Human Development·Rikke Ruager-MartinNeena Modi
Nov 27, 2009·Seminars in Fetal & Neonatal Medicine·Kate J FitzsimonsUNKNOWN Centre for Maternal and Child Enquires
Nov 3, 2009·Seminars in Fetal & Neonatal Medicine·Eleanor Jarvie, Jane E Ramsay
Oct 16, 2009·Seminars in Fetal & Neonatal Medicine·W McGuireM Renfrew
Nov 10, 2009·Seminars in Fetal & Neonatal Medicine·Shahzya S HudaNaveed Sattar
Oct 13, 2009·Seminars in Fetal & Neonatal Medicine·Ingrid RowlandsLeonie Callaway
Jun 26, 2015·Birth Defects Research. Part A, Clinical and Molecular Teratology·Sura Alwan, Christina D Chambers
Dec 4, 2008·Advances in Pediatrics·Jaime L Frías, Enid Gilbert-Barness
Jul 16, 2008·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Hala S KhalilShazia N Subhani
Dec 13, 2006·American Journal of Surgery·Tuoc DaoTodd McCarty
Sep 16, 2003·Obesity Research·Marie I Cedergren, Bengt A J Källén

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