PMID: 7536313Dec 5, 1994Paper

Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro

Neuroscience Letters
H P TooG P Wilkin

Abstract

The presence of mRNA transcripts coding for preprotachykinin-A and the substance P receptor in cultured astrocytes is demonstrated by a combination of reverse transcription/polymerase chain reaction (PCR) and Southern blotting. These findings showed that astrocytes in culture are capable of synthesing both the precursor of substance P (preprotachykinin-A) and the cognate receptor, substance P receptor (NK1). The simultaneous presence of both the ligand (substance P) and the receptor (NK1) may indicate an autocrine nature of astrocyte communication.

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Citations

Jan 17, 2007·Psychopharmacology·Younglim LeeAnantha Shekhar
Oct 31, 2003·Trends in Neurosciences·Ruud UbinkTomas Hökfelt
Sep 12, 2008·Current Opinion in Anaesthesiology·Ke Ren, Ronald Dubner
Feb 22, 2002·Glia·Amy RasleyIan Marriott
Feb 8, 2019·Plant Biology·N E Grulke, R L Heath
Jul 19, 2000·Journal of Neurochemistry·P D WalkerM J Bannon
Jun 5, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Vinita S ChauhanIan Marriott
Mar 7, 2020·Scientific Reports·Haissa Oliveira BritoAleksander Roberto Zampronio

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