PMID: 15374232May 1, 1995Paper

Presbyopia - a maverick of human aging

Archives of Gerontology and Geriatrics
B K Pierscionek, R A Weale

Abstract

The aim of this study was to examine the extent to which the age-related variations of properties of the human lens may be able to account for presbyopia. Dimensionless linear regressions were calculated for age-related biological functions with special reference to ocular and lenticular ones. Their intercepts on the x-(age-)axis are compared, and their distribution is analyzed. An analysis was made of the effect of the growth of the lens on the relation between its shape and the proximal zonular anchorages on the one hand and the age-related variation of the angle between the zonule and the equatorial plane of the lens. The lens is not unusual in seeming to have evolved in support of a life-span of about 120 years. Presbyopia, however, fails to fit into the general picture and this is hypothesized to result from lenticular growth and a combination of factors which are not all governed by senescence. The potential involvement of the root of the iris throws an interesting light on the apparently worldwide variation of the condition.

References

Mar 1, 1979·Experimental Eye Research·P N Farnsworth, S E Shyne
Jul 1, 1975·Journal of Gerontology·T FurukawaS Takasugi
Feb 1, 1992·Mechanisms of Ageing and Development·S TammJ W Rohen
Jan 1, 1991·Vision Research·G W van Alphen, W P Graebel
Mar 31, 1990·Mechanisms of Ageing and Development·R A Weale
Jan 1, 1989·Vision Research·J F KoretzP A Goeckner
Jan 1, 1986·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·R A Weale
Mar 7, 1985·Journal of Theoretical Biology·J Perkkiö, R Keskinen
Aug 1, 1974·Experimental Eye Research·N Brown
Mar 1, 1969·The Journal of Physiology·R F Fisher
Jan 1, 1995·Experimental Eye Research·R Weale
Jun 1, 1993·Mechanisms of Ageing and Development·R A Weale
Feb 1, 1953·A.M.A. Archives of Ophthalmology·A DE ROETTH
Jan 1, 1956·American Journal of Optometry and Archives of American Academy of Optometry·D HAMASAKIE MARG

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Citations

Jan 1, 1995·Documenta Ophthalmologica. Advances in Ophthalmology·B K Pierscionek, R A Weale
Jul 3, 2008·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M Baumeister, T Kohnen
Mar 1, 1995·Experimental Eye Research·B K Pierscionek
Sep 23, 2003·Survey of Ophthalmology·Robert Alexander Weale
Jul 1, 1997·Mechanisms of Ageing and Development·R A Weale
Feb 14, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·David B Elliott, Alison Green
Jun 23, 2007·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Hema Radhakrishnan, W Neil Charman
Sep 3, 2008·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Kathryn RichdaleKarla Zadnik
Oct 30, 2010·Journal of Cataract and Refractive Surgery·Dominique Van de SompelAlexander J Smits
Mar 14, 2008·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·W Neil Charman
Jun 1, 1997·Experimental Eye Research·B K Pierscionek
Sep 25, 1998·Vision Research·J A Mordi, K J Ciuffreda
Apr 16, 1998·Vision Research·A Glasser, M C Campbell
Sep 29, 2006·Computer Methods and Programs in Biomedicine·A AbolmaaliT Le
Dec 9, 1998·The American Journal of Physiology·M A CroftL Z Bito
Nov 16, 2018·Progress in Retinal and Eye Research·Kehao Wang, Barbara K Pierscionek

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