Prescription of potentially inappropriate medications among older people with intellectual disability: a register study

BMC Pharmacology & Toxicology
A AxmonPatrik Midlöv

Abstract

Older people have a greater disease burden and are more likely than younger to be prescribed medications. They are also more sensitive to adverse effects. With this in mind, a range of medications have been suggested inappropriate in this population. People with intellectual disability (ID) have a higher disease burden than the general population, putting them at even greater risk of prescription of such medications. The aim of this study was to describe prescription of potentially inappropriate medications among older people with ID in relation to prescriptions among their age peers in the general population. We established an administrative cohort of people with ID (ID cohort; n = 7936), using a Swedish national register. A referent cohort from the general population (gPop) was matched one-to-one by sex and year of birth. Data regarding prescription of potentially inappropriate medications were collected from the Swedish prescribed drug register for the years 2006-2012. People with ID were more likely than the general population to be prescribed medications with anticholinergic effects, intermediate- or long-acting benzodiazepines, and antipsychotics at least once during the study period, and also had more number of years wit...Continue Reading

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Citations

Sep 23, 2020·Journal of Intellectual Disability Research : JIDR·L R CharlotJ L McLaren
Sep 25, 2020·Primary Health Care Research & Development·Rasa MikelytePatricia M Wilson
Nov 16, 2019·International Journal of Clinical Pharmacy·Anne Gerd GranasCecilie Johannessen Landmark

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