Prescription profile in patients with SARS-CoV-2 infection hospitalised in Aragon, Spain

European Journal of Hospital Pharmacy. Science and Practice
Adriana AlvarezMaría Bestué

Abstract

On 14 March 2020, a state of alarm was declared in Spain because of the pandemic of coronavirus disease (COVID-19). After 12 weeks from the beginning of the pandemic, the number of confirmed cases stoods at 5781 in Aragon: 46% hospitalised, 5% admitted to intensive care unit, and 15% died. The absence of controlled trials in SARS-CoV-2 infection and the fast progression of the disease has promoted the use of treatments with unproven potential benefit. The objective of this study is to define the prescription profile in patients with SARS-CoV-2 infection hospitalised in Aragon, Spain during the pandemic and its adaptation to the official recommendations. Descriptive retrospective study of the consumption and inpatient dispensation of drugs in a sample of COVID-19 infected inpatients (with positive PCR test result) admitted to hospitals of Aragon, between 1 March and 8 May 2020. Data were collected by an inpatient dispensation software program. 1482 positive COVID-19 patients were analysed: 54.9% male, median age 75 years (IQR 62-85); 12% were admitted to the intensive care unit. Median prescription: 13 active ingredients per patient (IQR 9-19). 73% (1093 patients) received hydroxychloroquine, lopinavir/ritonavir, or azithromycin...Continue Reading

References

Mar 21, 2020·Lancet·Puja MehtaUNKNOWN HLH Across Speciality Collaboration, UK
Apr 28, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Adarsh BhimrajYngve Falck-Ytter
May 12, 2020·JAMA : the Journal of the American Medical Association·Eli S RosenbergHoward A Zucker
May 29, 2020·Infectious Diseases and Therapy·David C FajgenbaumSheila K Pierson

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Citations

Jul 18, 2021·European Journal of Hospital Pharmacy. Science and Practice·Elien B UitvlugtEwoudt M W van de Garde

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