Presence and distribution of leptin and its receptor in the gut of adult zebrafish in response to feeding and fasting

Anatomia, histologia, embryologia
Olivia Garcia-SuarezMaria Levanti

Abstract

Leptin is an anorectic hormone secreted mainly by peripheral adipocytes but also by other central and peripheral tissues. It acts by means of a receptor called OB-R, influencing not only appetite and body mass but being also involved in many fields like endocrinology, metabolism and reproduction. Immunohistochemistry and qRT-PCR techniques were, respectively, used to demonstrate the presence of leptin and its receptor in the gut of adult zebrafish and to evaluate the leptin gene expression response to feeding and fasting. Immunoreactivity for the antibodies utilized was demonstrated in feeding but not in fasting fish, and the gene expression analysis corroborates the data obtained by immunohistochemistry. Therefore, all the obtained results support the hypothesis of the role of this hormone in food regulation in zebrafish.

References

Jul 18, 1995·Proceedings of the National Academy of Sciences of the United States of America·M MaffeiJ M Friedman
Oct 10, 1997·Endocrinology·R SeñarísF F Casanueva
Mar 26, 1998·Biochemical and Biophysical Research Communications·J J PotterF A Anania
Sep 2, 1998·Nature·A BadoM J Lewin
Jun 16, 2000·Molecular and Cellular Endocrinology·G HorevM Friedman-Einat
Nov 22, 2000·Animal Genetics·I C DunnI R Paton
Mar 27, 2001·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·B S ZhouP K Lam
Jul 4, 2001·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·S YaghoubianJ H Youson
Nov 1, 2002·General and Comparative Endocrinology·Richard L Londraville, Charles S Duvall
Apr 6, 2004·Science·Shirly PintoTamas L Horvath
Mar 9, 2006·The Journal of Endocrinology·N de PedroM J Delgado
Jan 11, 2007·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M D KlokM L Drent
Sep 20, 2007·Neuroendocrinology·Michael WilkinsonEhud Ur
Jun 10, 2008·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Koji MurashitaTadahide Kurokawa
Aug 30, 2008·Physiological Genomics·Robert E DrewBarrie D Robison
Mar 19, 2009·The Journal of Endocrinology·Marnix GorissenMark O Huising
Apr 14, 2009·General and Comparative Endocrinology·Peter KlingBjörn Thrandur Björnsson
Jun 16, 2009·General and Comparative Endocrinology·Tadahide Kurokawa, Koji Murashita
Feb 7, 2012·Brain Research·Domenico MagnoliAntonino Germanà
Jun 16, 2012·Journal of Biomedicine & Biotechnology·J R Goldsmith, Christian Jobin
Jul 31, 2012·General and Comparative Endocrinology·Qin LiuRichard L Londraville
Jan 19, 2013·Neuroscience Letters·E ViñaJ A Vega
Jul 13, 2013·Frontiers in Physiology·Mark R DalmanRichard L Londraville

❮ Previous
Next ❯

Citations

Dec 6, 2020·International Journal of Molecular Sciences·Nicole VerdileFulvio Gandolfi
Feb 16, 2021·Molecular and Cellular Endocrinology·Ayelén Melisa Blanco, José Luis Soengas
Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Giuseppe MontalbanoAntonino Germanà
Jun 6, 2021·General and Comparative Endocrinology·Gianmarco Del VecchioIvar Rønnestad
Aug 4, 2021·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Amrita BakshiUmesh Rai

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Related Papers

Revue médicale de la Suisse romande
F P Pralong
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
A EnjuanesA Díez-Pérez
General and Comparative Endocrinology
L S RAMASWAMI
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme
P LaharragueL Casteilla
© 2022 Meta ULC. All rights reserved