PMID: 2510528Nov 1, 1989Paper

Presence of the schistosome circulating anodic antigen (CAA) in urine of patients with Schistosoma mansoni or S. haematobium infections

The American Journal of Tropical Medicine and Hygiene
N De JongeA M Deelder

Abstract

We investigated the presence of the circulating anodic antigen (CAA) in the urine of schistosomiasis patients. This genus specific antigen was hitherto demonstrated only in the serum of schistosomiasis patients. The urine of 80 patients with Schistosoma mansoni infections, 33 patients with S. haematobium infections, and 2 patients with mixed S. haematobium and S. mansoni infections were screened by a quantitative enzyme-linked immunosorbent assay (ELISA). CAA was demonstrated in 81% of those with intestinal schistosomiasis and in 97% of those with urinary schistosomiasis. CAA titers were less than 1:0.2-1:51.2. Results were compared with circulating cathodic antigen (CCA) titers in urine obtained in an indirect hemagglutination assay (IHA). CCA was generally not detectable in the urine of patients with S. haematobium infection, but was demonstrated in the urine of 85% of the patients with S. mansoni infection. Both CAA titers and CCA titers correlated positively with the number of S. mansoni eggs excreted in the feces, but CAA titers did not show a significant correlation with the number of S. haematobium eggs in urine. Both antigen titers showed a moderate correlation with the serum CAA level in schistosomiasis mansoni. The di...Continue Reading

Citations

Nov 1, 1991·Transactions of the Royal Society of Tropical Medicine and Hygiene·N De JongeA M Deelder
Mar 12, 2015·The Cochrane Database of Systematic Reviews·Eleanor A OchodoMariska M G Leeflang
Nov 1, 1990·Transactions of the Royal Society of Tropical Medicine and Hygiene·N de JongeA M Deelder
Jul 1, 1995·Transactions of the Royal Society of Tropical Medicine and Hygiene·D De ClercqA Deelder
Feb 25, 1999·Memórias do Instituto Oswaldo Cruz·Y Pereira e SilvaA Rabello
Aug 12, 2004·Tropical Medicine & International Health : TM & IH·K M BosompemN Ohta
Mar 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·J DischA Rabello
Jul 18, 2014·PLoS Neglected Tropical Diseases·Charles Emile RamarokotoBirgitte Jyding Vennervald
Dec 21, 2017·The American Journal of Tropical Medicine and Hygiene·Jean T CoulibalyIsaac I Bogoch
Sep 14, 2004·Tropical Medicine & International Health : TM & IH·Kwabena M BosompemSomei Kojima
Feb 17, 1998·Transactions of the Royal Society of Tropical Medicine and Hygiene·K M BosompemS Kojima
Mar 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·P G KremsnerA M Deelder
Mar 23, 2021·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·Enas A El Saftawy
Oct 1, 1991·Clinical Microbiology Reviews·S E Maddison
Oct 1, 1994·Journal of Clinical Microbiology·L van EttenA M Deelder

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