Presentation of benefits and harms of antidepressants on websites: A cross-sectional study.

The International Journal of Risk & Safety in Medicine
Maryanne Demasi, Peter C Gøtzsche

Abstract

Many people use the Internet for obtaining information about their medications. To investigate whether information about antidepressants on popular websites reflects the scientific evidence and enables people to make informed choices. Cross-sectional study using a checklist with 14 predefined criteria of 39 websites from 10 countries. All 39 websites mentioned the benefits of antidepressants. Twenty-nine (74%) websites attributed depression to a "chemical imbalance" or claimed they could fix an imbalance. Sexual dysfunction was mentioned as a harmful effect on 23 (59%) websites while five (13%) mentioned emotional numbing. Twenty-five (64%) stated that antidepressants may cause increased suicidal ideation, but 23 (92%) of them contained incorrect information, and only two (5%) websites noted that the suicide risk is increased in people of all ages. Twenty-eight websites (72%) warned patients about withdrawal effects but only one stated that antidepressants can be addictive. None of the websites met our predefined criteria. The information was generally inaccurate and unhelpful and has potential to lead to inappropriate use and overuse of antidepressants and reduce the likelihood that people will seek better options for depressi...Continue Reading

References

Jun 1, 2000·The New England Journal of Medicine·R MoynihanS B Soumerai
Apr 4, 2002·Journal of General Internal Medicine·Joseph A DiazAnne W Moulton
Sep 3, 2002·The British Journal of Psychiatry : the Journal of Mental Science·David OwensAllan House
Jan 29, 2003·The Annals of Pharmacotherapy·Michelle M KooParisa Aslani
Feb 8, 2006·Archives of Pediatrics & Adolescent Medicine·Rachel Levinson-CastielGil Klinger
Jul 4, 2006·Journal of Medical Ethics·L McHenry
Sep 4, 2009·Current Opinion in Pediatrics·Hiroki Mishina, John I Takayama
Mar 3, 2010·The British Journal of Psychiatry : the Journal of Mental Science·Pim CuijpersGerhard Andersson
Jul 10, 2010·Psychotherapy and Psychosomatics·H Edmund PigottJohn J Boren
May 15, 2013·Acta Psychiatrica Scandinavica·J Read, A Cain
May 22, 2013·Journal of Affective Disorders·Pamela D PilkingtonAnthony F Jorm
Jun 19, 2014·The New England Journal of Medicine·Krista F HuybrechtsSonia Hernández-Díaz
Feb 28, 2015·Psychotherapy and Psychosomatics·Giovanni A FavaEmanuela Offidani
Apr 23, 2015·BMJ : British Medical Journal·David Healy
Oct 13, 2016·Journal of the Royal Society of Medicine·Andreas Ø BielefeldtPeter C Gøtzsche
Mar 2, 2017·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Emma MaundPeter C Gøtzsche
Jun 20, 2017·Journal of Affective Disorders·G M GoodwinJ Laredo
Oct 19, 2017·Journal of the Royal Society of Medicine·Peter C Gøtzsche, Pernille K Gøtzsche

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Citations

May 24, 2020·The International Journal of Risk & Safety in Medicine·Peter C Gøtzsche, Olivia Dinnage
Jun 23, 2020·The International Journal of Risk & Safety in Medicine·Maxine Gossell-Williams

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Methods Mentioned

BETA
cognitive behavioural therapy

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