Presentation of M4 acute myeloid leukemia in anuric renal failure with hyperuricemia and enlarged kidneys

Journal of Pediatric Hematology/oncology
Jennifer Duda, Seymour Zoger

Abstract

Extramedullary acute myeloid leukemia (AML) is not uncommon. It has been shown to involve the kidneys in most postmortem cases but is most often clinically insignificant. By contrast, acute tumor lysis syndrome is rare in AML, especially at initial diagnosis. The authors report the management of a patient with AML who had acute tumor lysis syndrome that was probably potentiated by renal leukemia and resulted in renal failure. This patient achieved remission with dose-modified induction chemotherapy administered while he was dialysis-dependent.

References

Oct 30, 1975·Virchows Archiv. A, Pathological Anatomy and Histology·E W Schwarze
Jul 1, 1976·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·K AtkinsonT J McElwain
Nov 1, 1992·Leukemia & Lymphoma·D R Fleming, M A Doukas
Aug 1, 1983·International Journal of Radiation Oncology, Biology, Physics·L Y ChakR S Cox
Apr 1, 1980·The American Journal of Medicine·L F CohenJ L Ziegler
Oct 1, 1994·American Journal of Hematology·A M Jasek, H J Day
Feb 1, 1993·The American Journal of Medicine·K R Hande, G C Garrow
Feb 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J C ByrdC D Bloomfield
Apr 8, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M HaasW Druml
Mar 1, 2000·Journal of Pediatric Hematology/oncology·R D JenkinR Sabbah

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Citations

Sep 4, 2014·The American Journal of Case Reports·Elliot B TapperDimitrios Tzachanis
Jan 7, 2020·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Sae ArataniShuichi Tsuruoka
Dec 3, 2011·Nucleosides, Nucleotides & Nucleic Acids·Ayako NagaiKousaku Matsubara
Aug 1, 2013·Clinical Kidney Journal·Khai Yang OoiSolomon Menahem
May 11, 2019·BMC Genomics·Sora YoonDougu Nam
Nov 15, 2002·European Journal of Haematology·M D SeftelT J Nevill
Apr 24, 2003·The Annals of Pharmacotherapy·Jack T SekiDavid M C Sutton

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