Preservation of ejaculatory function by reconstruction of the canine hypogastric nerve

Journal of Neurosurgery
K KiharaH Oshima

Abstract

The hypogastric nerve (HGN) plays a crucial role in the primary functions of ejaculation: sperm transport through the vas deferens, secretion of prostatic fluid, and bladder neck closure. This study was undertaken to explore the possibility of restoring HGN function to the seminal tract and preserving its cross-innervation mechanism to the seminal tract after HGN-HGN reattachment. Responses of the vas deferens/epididymis, prostate, and bladder neck to electrical stimulation of the lumbar splanchnic nerve (LSN) or the HGN and occurrence of antegrade ejaculation as a result of manual penile stimulation were examined in dogs that had undergone HGN-HGN reattachment. Eighteen months after the procedure had been performed bilaterally, 23 LSNs were electrically stimulated. In 17 LSNs this stimulation elicited elevation of vasal pressure (12 nerves bilaterally); in 18 LNs, bladder neck pressure; and in 15 LSNs, prostate contraction. After retransection of the right HGN in the dogs that had undergone HGN-HGN reattachment, 11 right-sided LSNs were stimulated; in seven LSNs, the stimulation elicited elevation of vasal pressure (five bilaterally), in seven bladder neck pressure, and in six prostate contraction. Twelve left-sided LSNs were ...Continue Reading

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Citations

Feb 15, 2001·Neurourology and Urodynamics·K KiharaY Inoue
Aug 23, 2002·Pharmacology & Therapeutics·S VenturaFrederick Mitchelson
Mar 29, 2001·Autonomic Neuroscience : Basic & Clinical·T KobayashiK Sato
May 4, 2011·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Kumiko YamaguchiKeiichi Akita
Nov 17, 1998·Microscopy Research and Technique·K KiharaH Oshima
Jun 1, 2000·International Journal of Urology : Official Journal of the Japanese Urological Association·K Kihara
Oct 16, 2003·Current Opinion in Urology·Suzanne M Biers, Alison F Brading

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