PMID: 36633Jan 1, 1978

Preservation of platelet viability and function during storage of concentrates

Progress in Clinical and Biological Research
S J Slichter

Abstract

It has now been substantiated that the viability and function of concentrated platelets stored for 72 hours are best preserved at a storage temperature of 22 degrees C rather than 4 degrees C. However, in order to preserve viability at 22 degrees C several other conditions must be met and maintained, namely, an appropriate storage bag (Fenwal's PL-146, McGaw or Cutter's CL-2383), constant gentle agitation with a platform shaker, CPD anticoagulation, and a platelet concentration of less than 1.6 x 10(12)/liter. Unfortunately, in vitro parameters which can accurately assess stored platelet viability and function are not reliable.

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