Preserving Healthy Muscle during Weight Loss.

Advances in Nutrition
Edda CavaBettina Mittendorfer

Abstract

Weight loss is the cornerstone of therapy for people with obesity because it can ameliorate or completely resolve the metabolic risk factors for diabetes, coronary artery disease, and obesity-associated cancers. The potential health benefits of diet-induced weight loss are thought to be compromised by the weight-loss-associated loss of lean body mass, which could increase the risk of sarcopenia (low muscle mass and impaired muscle function). The objective of this review is to provide an overview of what is known about weight-loss-induced muscle loss and its implications for overall physical function (e.g., ability to lift items, walk, and climb stairs). The currently available data in the literature show the following: 1) compared with persons with normal weight, those with obesity have more muscle mass but poor muscle quality; 2) diet-induced weight loss reduces muscle mass without adversely affecting muscle strength; 3) weight loss improves global physical function, most likely because of reduced fat mass; 4) high protein intake helps preserve lean body and muscle mass during weight loss but does not improve muscle strength and could have adverse effects on metabolic function; 5) both endurance- and resistance-type exercise h...Continue Reading

Associated Clinical Trials

Apr 19, 2021·Boštjan Jakše, Boštjan Jakše

Citations

Jul 18, 2018·Obesity Facts·Rocco BarazzoniRoberto Vettor
Jan 11, 2020·American Journal of Respiratory and Critical Care Medicine·Stephen H WangRichard J Schwab
May 21, 2019·Expert Review of Endocrinology & Metabolism·Andrew GrannellCarel W le Roux
Aug 18, 2020·Journal of Nutrition and Metabolism·Boštjan JakšeNataša Fidler Mis
Apr 17, 2018·Advances in Nutrition·Connie W Bales, Kathryn N Porter Starr
Jun 25, 2019·The Journal of Nutrition, Health & Aging·C WoolleyC Horwood
Aug 9, 2020·Reviews in Endocrine & Metabolic Disorders·Rocco Barazzoni, Gianluca Gortan Cappellari
Aug 18, 2020·Reviews in Endocrine & Metabolic Disorders·Felipe F CasanuevaMiguel A Martinez-Olmos
Sep 19, 2020·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Leo Sungwong ChoiSang-Ku Yoo
Apr 17, 2020·European Geriatric Medicine·Michelle BarrettAnthony Villani
Mar 20, 2019·International Journal of Environmental Research and Public Health·Mary L GreaneyDeborah Riebe
Jun 12, 2019·Nutrients·Maria L PetroniGiulio Marchesini
Apr 3, 2020·BMC Musculoskeletal Disorders·Pedro L ValenzuelaAlessandro Sartorio
Jan 9, 2021·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Kara L Hall
Feb 3, 2021·Obesity·Andrew GrannellCarel W le Roux
Dec 6, 2020·Joint, Bone, Spine : Revue Du Rhumatisme·Kristine GodziukMary Forhan
Mar 9, 2021·Frontiers in Physiology·Fabrice BertileSylvain Giroud
Mar 18, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Paola Gonzalo-EncaboChristine M Friedenreich
May 28, 2019·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·G MigetG Amarenco
May 1, 2021·International Journal of Environmental Research and Public Health·Ladislav PilařRoman Kvasnička
Jul 1, 2021·Journal of the International Society of Sports Nutrition·Laurin Alexandra ConlinBill I Campbell
Jul 3, 2021·Nutrients·Ladislav PilařIvana Tichá
Aug 6, 2021·Nutrition Research and Practice·Hyeon-Ju PakJung-Eun Yim
Jul 31, 2021·Diabetes/metabolism Research and Reviews·Rebecca S GoldMatthew A Allison

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.